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Design and evaluation of a microcantilever aptasensor

Lim,YC, Kouzani,AZ, Duan,W, Dai,XJ, Kaynak,A and Mair,D 2014, Design and evaluation of a microcantilever aptasensor, in ISCAS 2014 : Proceedings of the 2014 IEEE International Symposium on Circuits and Systems, IEEE, Piscataway, N.J., pp. 221-224, doi: 10.1109/ISCAS.2014.6865105.

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Title Design and evaluation of a microcantilever aptasensor
Author(s) Lim,YC
Kouzani,AZ
Duan,W
Dai,XJ
Kaynak,A
Mair,D
Conference name IEEE International Symposium on Circuits and Systems (2014 : Melbourne, Victoria)
Conference location Melbourne, Victoria
Conference dates 1-5 Jun. 2014
Title of proceedings ISCAS 2014 : Proceedings of the 2014 IEEE International Symposium on Circuits and Systems
Editor(s) [Unknown]
Publication date 2014
Conference series IEEE International Symposium on Circuits and Systems
Start page 221
End page 224
Total pages 4
Publisher IEEE
Place of publication Piscataway, N.J.
Keyword(s) aptasensor
detection
microcantilever
Summary Aptamers enhance flexibility in biosensor design. An aptasensor employs aptamers as a biological recognition element for biosensing. This paper presents design, fabrication, and evaluation of a microcantilever aptasensor. To identify and avoid potential bottlenecks in the aptasensor design, the parameters of the aptasensor are investigated through modelling and simulation. Next, thin SU-8 microcantilevers are fabricated to form the aptasensor. Characterization of the fabricated aptasensor is presented. Next, a plasma-based surface funtionalisation method is used to immobilize aptamers on the atasensor. Finally, an evaluation of the performance of the aptasensor is performed through detection of thrombin molecules. The evaluation results are presented and discussed. © 2014 IEEE.
ISBN 9781479934324
ISSN 0271-4310
Language eng
DOI 10.1109/ISCAS.2014.6865105
Field of Research 090602 Control Systems, Robotics and Automation
091306 Microelectromechanical Systems (MEMS)
Socio Economic Objective 861502 Medical Instruments
HERDC Research category E1 Full written paper - refereed
ERA Research output type E Conference publication
Copyright notice ©2014, Institute of Electrical and Electronics Engineers Inc.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30070560

Document type: Conference Paper
Collection: School of Engineering
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