Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts

Moore, Eileen M., Ames, David, Mander, Alistair G., Carne, Ross P., Brodaty, Henry, Woodward, Michael C., Boundy, Karyn, Ellis, Kathryn A., Bush, Ashley I., Faux, Noel G., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Szoeke, Cassandra and Watters, David A. 2014, Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts, Journal of alzheimer's disease, vol. 39, no. 3, pp. 661-668, doi: 10.3233/JAD-131265.

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Title Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts
Author(s) Moore, Eileen M.
Ames, David
Mander, Alistair G.
Carne, Ross P.
Brodaty, Henry
Woodward, Michael C.
Boundy, Karyn
Ellis, Kathryn A.
Bush, Ashley I.
Faux, Noel G.
Martins, Ralph N.
Masters, Colin L.
Rowe, Christopher C.
Szoeke, Cassandra
Watters, David A.ORCID iD for Watters, David A. orcid.org/0000-0002-5742-8417
Journal name Journal of alzheimer's disease
Volume number 39
Issue number 3
Start page 661
End page 668
Total pages 7
Publisher IOS Press
Place of publication Amsterdam, The Netherlands
Publication date 2014
ISSN 1875-8908
Keyword(s) Aged
Alzheimer's disease
cognition
folic acid
vitamin B12
Science & Technology
Life Sciences & Biomedicine
Neurosciences
Neurosciences & Neurology
BASE-LINE CHARACTERISTICS
FOLIC-ACID INTAKE
ALZHEIMERS-DISEASE
SERUM FOLATE
LIFE-STYLE
HOMOCYSTEINE
POPULATION
FORTIFICATION
IMPAIRMENT
DECLINE
Summary Folate fortification of food aims to reduce the number of babies born with neural tube defects, but has been associated with cognitive impairment when vitamin B12 levels are deficient. Given the prevalence of low vitamin B12 levels among the elderly, and the global deployment of food fortification programs, investigation of the associations between cognitive impairment, vitamin B12, and folate are needed.
Language eng
DOI 10.3233/JAD-131265
Field of Research 111403 Paediatrics
Socio Economic Objective 920501 Child Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, IOS Press
Persistent URL http://hdl.handle.net/10536/DRO/DU:30070712

Document type: Journal Article
Collection: School of Medicine
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