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Treatment Implications of Predominant Polarity and the Polarity Index: A Comprehensive Review.

Carvalho,AF, Quevedo,J, McIntyre,RS, Soeiro-de-Souza,MG, Fountoulakis,KN, Berk,M, Hyphantis,TN and Vieta,E 2014, Treatment Implications of Predominant Polarity and the Polarity Index: A Comprehensive Review., International Journal of Neuropsychopharmacology, vol. 18, no. 2, doi: 10.1093/ijnp/pyu079.

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Title Treatment Implications of Predominant Polarity and the Polarity Index: A Comprehensive Review.
Author(s) Carvalho,AF
Quevedo,J
McIntyre,RS
Soeiro-de-Souza,MG
Fountoulakis,KN
Berk,MORCID iD for Berk,M orcid.org/0000-0002-5554-6946
Hyphantis,TN
Vieta,E
Journal name International Journal of Neuropsychopharmacology
Volume number 18
Issue number 2
Publisher Oxford University Press (OUP)
Publication date 2014
ISSN 1469-5111
Keyword(s) bipolar disorder
maintenance
polarity index
predominant polarity
treatment
Summary Bipolar disorder (BD) is a serious and recurring condition that affects approximately 2.4% of the global population. About half of BD sufferers have an illness course characterized by either a manic or a depressive predominance. This predominant polarity in BD may be differentially associated with several clinical correlates. The concept of a polarity index (PI) has been recently proposed as an index of the antimanic versus antidepressive efficacy of various maintenance treatments for BD. Notwithstanding its potential clinical utility, predominant polarity was not included in the DSM-5 as a BD course specifier.
DOI 10.1093/ijnp/pyu079
Field of Research 110319 Psychiatry (incl Psychotherapy)
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2014, Oxford University Press (OUP)
Persistent URL http://hdl.handle.net/10536/DRO/DU:30071251

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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