The role of genetics in suicide and the link with major depression and alcoholism.

Mitchell,B, Mitchell,D and Berk,M 2000, The role of genetics in suicide and the link with major depression and alcoholism., International Journal of Psychiatry in Clinical Practice, vol. 4, no. 4, pp. 275-280, doi: 10.1080/13651500050517821.

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Title The role of genetics in suicide and the link with major depression and alcoholism.
Author(s) Mitchell,B
Mitchell,D
Berk,MORCID iD for Berk,M orcid.org/0000-0002-5554-6946
Journal name International Journal of Psychiatry in Clinical Practice
Volume number 4
Issue number 4
Start page 275
End page 280
Publisher Informa Healthcare
Place of publication England
Publication date 2000
ISSN 1365-1501
Keyword(s) Suicide Alcoholism Major Depression Genetics
Science & Technology
Life Sciences & Biomedicine
Psychiatry
PSYCHIATRY, SCI
suicide
alcoholism
major depression
genetics
TRYPTOPHAN-HYDROXYLASE GENE
CROSS-FOSTERING ANALYSIS
MONOAMINE METABOLITES
CEREBROSPINAL-FLUID
AFFECTIVE-DISORDERS
HUMAN-BRAIN
CO-TWINS
ASSOCIATION
BEHAVIOR
POLYMORPHISM
Summary A clear genetic influence in suicide has been established. In addition, both the serotonergic and noradrenergic systems appear to have a role in suicide, mood disorders and alcoholism. This paper reviews some of the genes that may possibly be involved in suicide and their link to major depression and alcoholism. The genes that are reviewed act on various enzymes within the serotonergic and catecholaminergic systems. With further study, these entities may form a spectrum along the same disease process associated with variable expressivity of the responsible genes.
Language eng
DOI 10.1080/13651500050517821
Field of Research 0 Not Applicable
Socio Economic Objective 0 Not Applicable
HERDC Research category C2.1 Other contribution to refereed journal
Copyright notice ©2000, Informa Healthcare
Persistent URL http://hdl.handle.net/10536/DRO/DU:30071268

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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