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Fluoxetine treatment of acral lick dermatitis in dogs: a placebo-controlled randomized double blind trial.

Wynchank,D and Berk,M 1998, Fluoxetine treatment of acral lick dermatitis in dogs: a placebo-controlled randomized double blind trial., Depression and Anxiety, vol. 8, no. 1, pp. 21-23.

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Title Fluoxetine treatment of acral lick dermatitis in dogs: a placebo-controlled randomized double blind trial.
Author(s) Wynchank,D
Berk,MORCID iD for Berk,M orcid.org/0000-0002-5554-6946
Journal name Depression and Anxiety
Volume number 8
Issue number 1
Start page 21
End page 23
Publisher Wiley
Place of publication UNITED STATES
Publication date 1998
ISSN 1091-4269
Summary The aim of the study was to assess the efficacy and tolerability of fluoxetine treatment of acral lick dermatitis (ALD) in dogs and to investigate ALD as an animal model of obsessive-compulsive disorder (OCD). Sixty-three dogs with ALD were treated with fluoxetine 20 mg daily, or placebo, for 6 weeks. In the fluoxetine group, owners rated both appearance of the lesion (t = 10.2, df = 29, P < 0.0001) and licking behavior (t = 10.2, df = 29, P < 0.0001) as significantly improved by the end of the trial. Veterinarian-rated pre- and post-treatment photographs showed statistically significant improvement in the fluoxetine group (mean = 2.55). There were no significant changes in the placebo group as rated by owners and veterinarians. These results demonstrate the efficacy of fluoxetine in the treatment of ALD and lend further support to ALD as an animal model of OCD.
Language eng
Field of Research 0 Not Applicable
Socio Economic Objective 0 Not Applicable
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1998, Wiley
Persistent URL http://hdl.handle.net/10536/DRO/DU:30071422

Document type: Journal Article
Collection: School of Medicine
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