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Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance

Al-Ejeh,F, Staudacher,AH, Smyth,DR, Darby,JM, Denoyer,D, Tsopelas,C, Hicks,RJ and Brown,MP 2014, Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance, JNM : The journal of nuclear medicine, vol. 55, no. 5, pp. 772-779, doi: 10.2967/jnumed.113.130559.

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Title Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance
Author(s) Al-Ejeh,F
Staudacher,AH
Smyth,DR
Darby,JM
Denoyer,DORCID iD for Denoyer,D orcid.org/0000-0001-8932-5116
Tsopelas,C
Hicks,RJ
Brown,MP
Journal name JNM : The journal of nuclear medicine
Volume number 55
Issue number 5
Start page 772
End page 779
Total pages 9
Publisher Society of Nuclear Medicine
Place of publication New York, N.Y.
Publication date 2014-05-01
ISSN 1535-5667
Keyword(s) APOMAB
DAB4
La
apoptosis
chemotherapy
therapy response
Animals
Antibodies, Monoclonal, Murine-Derived
Antineoplastic Agents
Autoantigens
Binding, Competitive
Cell Proliferation
DNA Breaks, Double-Stranded
Female
Flow Cytometry
Humans
Jurkat Cells
Lymphoma
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Neoplasm Transplantation
Prostatic Neoplasms
Protein Binding
Radionuclide Imaging
Ribonucleoproteins
Thymocytes
Thymus Neoplasms
Treatment Outcome
Summary Early identification of tumor responses to treatment is crucial for devising more effective and safer cancer treatments. No widely applicable, noninvasive method currently exists for specifically detecting tumor cell death after cytotoxic treatment and thus for predicting treatment outcomes.
Language eng
DOI 10.2967/jnumed.113.130559
Field of Research 111201 Cancer Cell Biology
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Society of Nuclear Medicine
Persistent URL http://hdl.handle.net/10536/DRO/DU:30071642

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