Allergen to allergy: identifying epithelial endocytotic pathways of peanut allergens

Price, D., Ackland, L. and Suphioglu, C. 2014, Allergen to allergy: identifying epithelial endocytotic pathways of peanut allergens, in EAACI 2014 : Proceedings of the European Academy of Allergy and Clinical Immunology Congress, Wiley, Chichester, Eng., pp. 266-266, doi: 10.1111/all.12476.

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Title Allergen to allergy: identifying epithelial endocytotic pathways of peanut allergens
Author(s) Price, D.
Ackland, L.
Suphioglu, C.ORCID iD for Suphioglu, C. orcid.org/0000-0003-0101-0668
Conference name European Academy of Allergy and Clinical Immunology. Annual Congress (2014 : Copenhagen, Denmark)
Conference location Copenhagen, Denmark
Conference dates 7-11 Jun. 2014
Title of proceedings EAACI 2014 : Proceedings of the European Academy of Allergy and Clinical Immunology Congress
Publication date 2014
Series Allergy
Start page 266
End page 266
Total pages 1
Publisher Wiley
Place of publication Chichester, Eng.
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Allergy
Immunology
Summary Food allergy has continued to rise over the past few decades. Theincreasing occurrence of sensitivity to certain foods remains to be identified, and the allergen-epithelial interaction in particular remains elusive. Peanuts in particular are still one of the highest contributors of anaphylaxis after ingestion of a food allergen. Previous findings by our research group observed that peanut allergens were able to cross the Caco-2 cell culture model of the intestinal epithelium. Specifically, the major peanut allergens Ara h 1, Ara h 2 and Ara h 3, as well as Ara h 6. The direction of this research has deepened into identifying the mechanism by which the Caco-2 monolayers uptake peanut allergens, specifically by endocytosis. Here, we aim to further our understanding about the pathway from allergen to allergy.
Notes Published in Allergy, Special Issue: Abstracts from the European Academy of Allergy and Clinical Immunology Congress, 7–11 June 2014, Copenhagen, Denmark, September 2014, Volume 69, Issue Supplement s99, Pages 1–646
ISSN 0105-4538
Language eng
DOI 10.1111/all.12476
Field of Research 110799 Immunology not elsewhere classified
1107 Immunology
Socio Economic Objective NA
HERDC Research category EN.1 Other conference paper
ERA Research output type E Conference publication
Copyright notice ©2014, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30071990

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