You are not logged in.

Discovering the effects of omega-6 fatty acids on allergy using a HEK-Blue cell line

Ahmed, N. and Suphioglu, C. 2014, Discovering the effects of omega-6 fatty acids on allergy using a HEK-Blue cell line, in EAACI 2014 : Proceedings of the European Academy of Allergy and Clinical Immunology Congress, Wiley, London, Eng., pp. 534-534, doi: 10.1111/all.12476.

Attached Files
Name Description MIMEType Size Downloads

Title Discovering the effects of omega-6 fatty acids on allergy using a HEK-Blue cell line
Author(s) Ahmed, N.
Suphioglu, C.
Conference name European Academy of Allergy and Clinical Immunology. Annual Congress (2014 : Copenhagen, Denmark)
Conference location Copenhagen, Denmark
Conference dates 7-11 Jun. 2014
Title of proceedings EAACI 2014 : Proceedings of the European Academy of Allergy and Clinical Immunology Congress
Publication date 2014
Start page 534
End page 534
Total pages 1
Publisher Wiley
Place of publication London, Eng.
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Allergy
Immunology
Summary In recent times, allergy has become a financial, physical and psychological burden to the society as a whole. Allergic reactions can result in life-threatening situations causing morbidity and high economic cost. Therefore, more effective reagents are needed for allergy treatment. Omega-6 fatty acids have gained attention in allergic studies mainly due to their inflammatory properties. Literature suggests that a causal relationship exists between the intake of omega-6 fatty acids such as DPA and AA and atopic individuals suffering from allergies. In an allergic cascade, cytokines IL-4 and IL-13 bind to IL-4 receptor (IL-4R), which activates the STAT6 phosphorylation pathway leading to gene activation of allergen-specific IgE production by B cells. Consequently, IgE production leads to clinical symptoms of allergy. The overall aim of this study is to characterise DPA and AA and their effects on IgE production.
ISSN 0105-4538
Language eng
DOI 10.1111/all.12476
Field of Research 110799 Immunology not elsewhere classified
1107 Immunology
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category EN.1 Other conference paper
ERA Research output type E Conference publication
Copyright notice ©2014, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30071995

Document type: Conference Paper
Collection: School of Life and Environmental Sciences
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 0 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 19 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Fri, 28 Aug 2015, 13:42:16 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.