Blood pressure and cognitive function: the role of central aortic and brachial pressures

Pase,MP, Stough,C, Grima,NA, Harris,E, Macpherson,H, Scholey,AB and Pipingas,A 2013, Blood pressure and cognitive function: the role of central aortic and brachial pressures, Psychological science, vol. 24, no. 11, pp. 2173-2181, doi: 10.1177/0956797613488602.

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Title Blood pressure and cognitive function: the role of central aortic and brachial pressures
Author(s) Pase,MP
Macpherson,HORCID iD for Macpherson,H
Journal name Psychological science
Volume number 24
Issue number 11
Start page 2173
End page 2181
Total pages 9
Publisher Sage
Place of publication London, Eng.
Publication date 2013-11-01
ISSN 1467-9280
Keyword(s) blood pressure
central pressure
cognitive ability
cognitive neuroscience
nervous system disorders
pulse-pressure amplification
Social Sciences
Psychology, Multidisciplinary
Summary Central (aortic) blood pressures differ from brachial pressures and may be more relevant to the study of cognitive function, given that blood is delivered to the brain through the central large arteries. Pulse-pressure amplification reflects the augmentation of blood pressure between the central and peripheral arteries, which diminishes with aging. We aimed to determine the association between central blood pressure and cognitive function in independently living adults aged 20 to 82 years (N = 493). In adjusted regression models, higher central systolic pressure and higher central pulse pressure were each associated with poorer processing speed, Stroop processing, and recognition memory. Lower amplification was associated with poorer Stroop processing, working memory, and recognition memory. Higher brachial systolic pressure and brachial pulse pressure were both associated with poorer Stroop processing. In summary, central pressures and amplification were sensitive indicators of cognitive aging, predicting aspects of cognitive performance not predicted by brachial blood pressure.
Language eng
DOI 10.1177/0956797613488602
Field of Research 170299 Cognitive Science not elsewhere classified
Socio Economic Objective 920410 Mental Health
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2013, SAGE Publishing
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Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
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