Glucose enhancement of recognition memory: differential effects on effortful processing but not aspects of 'remember-know' responses

Scholey,A, Macpherson,H, Sünram-Lea,S, Elliott,J, Stough,C and Kennedy,D 2013, Glucose enhancement of recognition memory: differential effects on effortful processing but not aspects of 'remember-know' responses, Neuropharmacology, vol. 64, pp. 544-549, doi: 10.1016/j.neuropharm.2012.06.030.

Attached Files
Name Description MIMEType Size Downloads

Title Glucose enhancement of recognition memory: differential effects on effortful processing but not aspects of 'remember-know' responses
Author(s) Scholey,A
Macpherson,HORCID iD for Macpherson,H orcid.org/0000-0002-3603-9359
Sünram-Lea,S
Elliott,J
Stough,C
Kennedy,D
Journal name Neuropharmacology
Volume number 64
Start page 544
End page 549
Total pages 6
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2013-01
ISSN 1873-7064
Keyword(s) Familiarity
Hippocampus
Mental effort
Recognition memory
Recollection
Science & Technology
Life Sciences & Biomedicine
Neurosciences
Pharmacology & Pharmacy
Neurosciences & Neurology
SPONTANEOUS-ALTERNATION PERFORMANCE
HEALTHY-YOUNG ADULTS
EPISODIC MEMORY
BLOOD-GLUCOSE
ACETYLCHOLINE-RELEASE
COGNITIVE PERFORMANCE
TASK-DIFFICULTY
Summary The administration of a glucose drink has been shown to enhance cognitive performance with effect sizes comparable with those from pharmaceutical interventions in human trials. In the memory domain, it is currently debated whether glucose facilitation of performance is due to differential targeting of hippocampal memory or whether task effort is a more important determinant. Using a placebo-controlled, double-blind, crossover 2(Drink: glucose/placebo) × 2(Effort: ± secondary task) design, 20 healthy young adults' recognition memory performance was measured using the 'remember-know' procedure. Two high effort conditions (one for each drink) included secondary hand movements during word presentation. A 25 g glucose or 30 mg saccharine (placebo) drink was consumed 10 min prior to the task. The presence of a secondary task resulted in a global impairment of memory function. There were significant Drink × Effort interactions for overall memory accuracy but no differential effects for 'remember' or 'know' responses. These data suggest that, in some circumstances, task effort may be a more important determinant of the glucose facilitation of memory effect than hippocampal mediation. This article is part of a Special Issue entitled 'Cognitive Enhancers'.
Language eng
DOI 10.1016/j.neuropharm.2012.06.030
Field of Research 170299 Cognitive Science not elsewhere classified
Socio Economic Objective 920411 Nutrition
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2013, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30073127

Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 13 times in TR Web of Science
Scopus Citation Count Cited 12 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 379 Abstract Views, 1 File Downloads  -  Detailed Statistics
Created: Fri, 08 May 2015, 12:08:04 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.