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Zebrafish as a model for leukemia and other hematopoietic disorders

Rasighaemi, Parisa, Basheer, Faiza, Liongue, Clifford and Ward, Alister C. 2015, Zebrafish as a model for leukemia and other hematopoietic disorders, Journal of hematology & oncology, vol. 8, no. 29, pp. 1-10, doi: 10.1186/s13045-015-0126-4.

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Title Zebrafish as a model for leukemia and other hematopoietic disorders
Author(s) Rasighaemi, Parisa
Basheer, Faiza
Liongue, Clifford
Ward, Alister C.ORCID iD for Ward, Alister C. orcid.org/0000-0001-7945-7975
Journal name Journal of hematology & oncology
Volume number 8
Issue number 29
Start page 1
End page 10
Total pages 10
Publisher BioMed Central
Place of publication London, Eng.
Publication date 2015
ISSN 1756-8722
Keyword(s) Leukemia
Myelodysplastic syndrome
Myeloproliferative disorder
Zebrafish
Science & Technology
Life Sciences & Biomedicine
Oncology
Hematology
ACUTE LYMPHOBLASTIC-LEUKEMIA
ACUTE MYELOID-LEUKEMIA
T-CELL LEUKEMIA
TRANSGENIC ZEBRAFISH
STEM-CELLS
DEFINITIVE HEMATOPOIESIS
CONSTITUTIVE ACTIVATION
MYELOGENOUS LEUKEMIA
ADULT ZEBRAFISH
MYC ONCOGENE
Summary Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.
Language eng
DOI 10.1186/s13045-015-0126-4
Field of Research 111299 Oncology and Carcinogenesis not elsewhere classified
Socio Economic Objective 920199 Clinical Health (Organs
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, BioMed Central
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30073147

Document type: Journal Article
Collections: School of Medicine
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Created: Mon, 31 Aug 2015, 14:16:30 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.