Coronary obstruction following transcatheter aortic valve implantation: a systematic review

Ribeiro, Henrique Barbosa, Nombela-Franco, Luis, Urena, Marina, Mok, Michael, Pasian, Sergio, Doyle, Daniel, DeLarochellière, Robert, Côté, Mélanie, Laflamme, Louis, DeLarochellière, Hugo, Allende, Ricardo, Dumont, Eric and Rodés-Cabau, Josep 2013, Coronary obstruction following transcatheter aortic valve implantation: a systematic review, JACC : cardiovascular interventions, vol. 6, no. 5, pp. 452-461, doi: 10.1016/j.jcin.2012.11.014.

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Title Coronary obstruction following transcatheter aortic valve implantation: a systematic review
Author(s) Ribeiro, Henrique Barbosa
Nombela-Franco, Luis
Urena, Marina
Mok, MichaelORCID iD for Mok, Michael
Pasian, Sergio
Doyle, Daniel
DeLarochellière, Robert
Côté, Mélanie
Laflamme, Louis
DeLarochellière, Hugo
Allende, Ricardo
Dumont, Eric
Rodés-Cabau, Josep
Journal name JACC : cardiovascular interventions
Volume number 6
Issue number 5
Start page 452
End page 461
Total pages 10
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2013-05
ISSN 1936-8798
Keyword(s) Aged
Aged, 80 and over
Aortic Valve Stenosis
Cardiac Catheterization
Chi-Square Distribution
Coronary Artery Disease
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Logistic Models
Percutaneous Coronary Intervention
Prosthesis Design
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome
Science & Technology
Life Sciences & Biomedicine
Cardiac & Cardiovascular Systems
Cardiovascular System & Cardiology
aortic stenosis
coronary obstruction
coronary occlusion
coronary stenosis
transcatheter aortic valve replacement
transcatheter heart valve
Summary OBJECTIVES: This study sought to evaluate, through a systematic review of the published data, the main baseline characteristics, management, and clinical outcomes of patients suffering coronary obstruction as a complication of transcatheter aortic valve implantation (TAVI).
BACKGROUND: Very few data exist on coronary obstruction after TAVI.
METHODS: Studies published between 2002 and 2012, with regard to coronary obstruction as a complication of TAVI, were identified with a systematic electronic search. Only the studies reporting data on the main baseline and procedural characteristics, management of the complication, and clinical outcomes were analyzed.
RESULTS: A total of 18 publications describing 24 patients were identified. Most (83%) patients were women, with a mean age of 83 ± 7 years and a mean logistic European System for Cardiac Operative Risk Evaluation score of 25.1 ± 12.0%. Mean left coronary artery (LCA) ostium height and aortic root width were 10.3 ± 1.6 mm and 27.8 ± 2.8 mm, respectively. Most patients (88%) had received a balloon-expandable valve, and coronary obstruction occurred more frequently in the LCA (88%). Percutaneous coronary intervention was attempted in 23 cases (95.8%) and was successful in all but 2 patients (91.3%). At 30-day follow-up, there were no cases of stent thrombosis or repeat revascularization, and the mortality rate was 8.3%.
CONCLUSIONS: Reported cases of coronary obstruction after TAVI occurred more frequently in women, in patients receiving a balloon-expandable valve, and the LCA was the most commonly involved artery. Percutaneous coronary intervention was a feasible and successful treatment in most cases. Continuous efforts should be made to identify the factors associated with this life-threatening complication to implement the appropriate measures for its prevention.
Language eng
DOI 10.1016/j.jcin.2012.11.014
Field of Research 110201 Cardiology (incl Cardiovascular Diseases)
1102 Cardiovascular Medicine And Haematology
Socio Economic Objective 920103 Cardiovascular System and Diseases
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2013, American College of Cardiology Foundation
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Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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