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Orally administered anti-cancer nanocarriers loaded with therapeutic proteins

Mahidhara, V.N.L.Ganesh 2012, Orally administered anti-cancer nanocarriers loaded with therapeutic proteins, PhD thesis, Institute for Frontier Materials, Deakin University.

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Title Orally administered anti-cancer nanocarriers loaded with therapeutic proteins
Author Mahidhara, V.N.L.Ganesh
Institution Deakin University
School Institute for Frontier Materials
Degree type Research doctorate
Degree name PhD
Thesis advisor Kanwar, JagatORCID iD for Kanwar, Jagat orcid.org/0000-0003-3728-9568
Kanwar (nee Kaur), Rupinder
Date submitted 2012-05
Keyword(s) alginate enclosed chitosan coated ceramic nanocarriers
cancer therapy
drug delivery systems
nanotechnology
Summary  Anti-cancerous ability of orally fed therapeutic proteins was potentiated by further strengthening their digestive resistance by means of nano encapsulation. In this regard, formulation of a novel polymer encapsulated ceramic anti-cancer nanocarriers (ACSC NCs) loaded with anti-cancer proteins (Fe-bLf and SurR9-C84A) were synthesized. These NCs were successfully evaluated for their anti-cancer efficacy in vitro and in nude mice bearing human cancers.
Language eng
Field of Research 100703 Nanobiotechnology
100709 Nanomedicine
Socio Economic Objective 920102 Cancer and Related Disorders
Description of original xix, 235 pages : illustrations, tables, graphs, some coloured
Dewey Decimal Classification 614.5999
Copyright notice ┬ęThe Author. All Rights Reserved
Free to Read? Yes
Free to Read Start Date 2014-05-25
Persistent URL http://hdl.handle.net/10536/DRO/DU:30073444

Document type: Thesis
Collections: Higher degree theses (full text)
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.