Breaking up prolonged sitting reduces resting blood pressure in overweight/obese adults

Larsen, R N, Kingwell, B A, Sethi, P, Cerin, E, Owen, N and Dunstan, D W 2014, Breaking up prolonged sitting reduces resting blood pressure in overweight/obese adults, Nutrition, metabolism, and cardiovascular diseases : NMCD, vol. 24, no. 9, pp. 976-982, doi: 10.1016/j.numecd.2014.04.011.

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Title Breaking up prolonged sitting reduces resting blood pressure in overweight/obese adults
Author(s) Larsen, R N
Kingwell, B A
Sethi, P
Cerin, E
Owen, N
Dunstan, D W
Journal name Nutrition, metabolism, and cardiovascular diseases : NMCD
Volume number 24
Issue number 9
Start page 976
End page 982
Total pages 7
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2014-09-01
ISSN 1590-3729
Keyword(s) Hypertension
Obesity
Physical activity
Sedentary behavior
Summary Abstract
Aim:
To compare the effect of 7 h of prolonged sitting on resting blood pressure with asimilar duration of sitting combined with intermittent brief bouts of light-intensity or moderate-intensity physical activity.
Methods and results:
Overweight/obeseadults(nZ19;aged45 e65years) were recruited for a randomized three-treatment crossover trial with a one-week washout between treatments: 1) uninterrupted sitting; 2) sitting with 2 min bouts of light-intensity walking at 3.2 km/h every 20 min;and, 3) sitting with 2 min bouts of moderate-intensity walking at between 5.8 and 6.4 km/h every 20 min. After an initial 2 h period seated, participants consumed a test meal (75 g carbohydrate,50 g fat) and completed each condition over the next 5 h. Resting blood pressure was assessed oscillometrically every hour as a single measurement, 5 min prior to each activity bout. GEE models were adjusted for sex, age, BMI, fasting blood pressure and treatment order. After adjustment for potential confounding variables, breaking up prolonged sitting with lightand moderate-intensity activity breaks was associated with lower systolic blood pressure [light:120

1 mmHg (estimated marginal mean

SEM),
P
Z
0.002; moderate: 121

1 mmHg,
P
Z
0.02], compared to uninterrupted sitting (123

1 mmHg). Diastolic blood pressure was also
signi
fi
cantly lower during both of the activity conditions (light: 76

1 mmHg,
P
Z
0.006; moder-
ate: 77

1mmHg,
P
Z
0.03) compared to uninterrupted sitting (79

1 mmHg). No significant between-condition differences were observed in mean arterial pressure or heart rate.
Conclusion:
Regularly breaking up prolonged sitting may reduce systolic and diastolic blood pressure.
Language eng
DOI 10.1016/j.numecd.2014.04.011
Field of Research 110602 Exercise Physiology
Socio Economic Objective 920401 Behaviour and Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30073453

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