Changes in corticomotor excitability and inhibition after exercise are influenced by hand dominance and motor demand

Teo, W. P., Rodrigues, J. P., Mastaglia, F. L. and Thickbroom, G. W. 2012, Changes in corticomotor excitability and inhibition after exercise are influenced by hand dominance and motor demand, Neuroscience, vol. 210, pp. 110-117, doi: 10.1016/j.neuroscience.2012.03.021.

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Title Changes in corticomotor excitability and inhibition after exercise are influenced by hand dominance and motor demand
Author(s) Teo, W. P.ORCID iD for Teo, W. P. orcid.org/0000-0003-3929-9778
Rodrigues, J. P.
Mastaglia, F. L.
Thickbroom, G. W.
Journal name Neuroscience
Volume number 210
Start page 110
End page 117
Total pages 11
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2012-05-17
ISSN 0306-4522
Keyword(s) Transcranial magnetic stimulation
Rhythmic finger movement
Corticomotor excitability
Handedness
Summary Previous studies on handedness have often reported functional asymmetries in corticomotor excitability (CME) associated with voluntary movement. Recently, we have shown that the degree of post-exercise corticomotor depression (PED) and increase in short-interval cortical inhibition (SICI) after a repetitive finger movement task was less when the task was performed at a maximal voluntary rate (MVR) than when it was performed at a submaximal sustainable rate (SR). In the current study, we have compared the time course of PED and SICI in the dominant (DOM) and nondominant (NDOM) hands after an MVR and SR finger movement task to determine the influence of hand dominance and task demand. We tracked motor-evoked potential (MEP) amplitude from the first dorsal interosseous muscle of the DOM and NDOM hand for 20 min after a 10-s index finger flexion-extension task at MVR and SR. For all hand-task combinations, we report a period of PED and increased SICI lasting for up to 8 min. We find that the least demanding task, one that involved index finger movement of the DOM hand at SR, was associated with the greatest change in PED and SICI from baseline (63.6±5.7% and 79±2%, P<0.001, PED and SICI, respectively), whereas the most demanding task (MVR of the NDOM hand) was associated with the least change from baseline (PED: 88.1±3.6%, SICI: 103±2%; P<0.001). Our findings indicate that the changes in CME and inhibition associated with repetitive finger movement are influenced both by handedness and the degree of demand of the motor task and are inversely related to task demand, being smallest for an MVR task of the NDOM hand and greatest for an SR task of the DOM hand. The findings provide additional evidence for differences in neuronal processing between the dominant and nondominant hemispheres in motor control.
Language eng
DOI 10.1016/j.neuroscience.2012.03.021
Field of Research 110699 Human Movement and Sports Science not elsewhere classified
Socio Economic Objective 929999 Health not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2012, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30073662

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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