Functionalized mesoporous silica nanoparticles with redox-responsive short-chain gatekeepers for agrochemical delivery.

Yi,Z, Hussain,HI, Feng,C, Sun,D, She,F, Rookes,JE, Cahill,DM and Kong,L 2015, Functionalized mesoporous silica nanoparticles with redox-responsive short-chain gatekeepers for agrochemical delivery., ACS Applied Materials & Interfaces, vol. 7, no. 18, pp. 9937-9946, doi: 10.1021/acsami.5b02131.

Attached Files
Name Description MIMEType Size Downloads

Title Functionalized mesoporous silica nanoparticles with redox-responsive short-chain gatekeepers for agrochemical delivery.
Author(s) Yi,Z
Hussain,HI
Feng,C
Sun,D
She,FORCID iD for She,F orcid.org/0000-0001-8191-0820
Rookes,JEORCID iD for Rookes,JE orcid.org/0000-0003-1479-2339
Cahill,DMORCID iD for Cahill,DM orcid.org/0000-0002-2556-0528
Kong,LORCID iD for Kong,L orcid.org/0000-0001-6219-3897
Journal name ACS Applied Materials & Interfaces
Volume number 7
Issue number 18
Start page 9937
End page 9946
Publisher American Chemical Society
Place of publication United States
Publication date 2015-05
ISSN 1944-8252
Keyword(s) agrochemical delivery system
decanethiol gatekeepers
mesoporous silica nanoparticles (MSNs)
redox-responsive gatekeepers
stimuli-response
Science & Technology
Technology
Nanoscience & Nanotechnology
Materials Science, Multidisciplinary
Science & Technology - Other Topics
Materials Science
CONTROLLED DRUG-DELIVERY
CONTROLLED PARTICLE-SIZE
COATED GOLD NANORODS
PLANT-CELL WALLS
SALICYLIC-ACID
CONTROLLED-RELEASE
GENE-EXPRESSION
INTRACELLULAR RELEASE
PORE-SIZE
ARABIDOPSIS
Summary The controlled release of salicylic acid (SA), a key phytohormone, was mediated by using a novel decanethiol gatekeeper system grafted onto mesoporous silica nanoparticles (MSNs). The decanethiol was conjugated only to the external surfaces of the MSNs through glutathione (GSH)-cleavable disulfide linkages and the introduction of a process to assemble gatekeepers only on the outer surface so that the mesopore area can be maintained for high cargo loading. Raman and nitrogen sorption isotherm analyses confirmed the successful linkage of decanethiol to the surface of MSNs. The in vitro release of SA from decanethiol gated MSNs indicated that the release rate of SA in an environment with a certain amount of GSH was significantly higher than that without GSH. More importantly, in planta experiments showed the release of SA from decanethiol gated MSNs by GSH induced sustained expression of the plant defense gene PR-1 up to 7 days after introduction, while free SA caused an early peak in PR-1 expression which steadily decreased after 3 days. This study demonstrates the redox-responsive release of a phytohormone in vitro and also indicates the potential use of MSNs in planta as a controlled agrochemical delivery system.
Language eng
DOI 10.1021/acsami.5b02131
Field of Research 060799 Plant Biology not elsewhere classified
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, American Chemical Society
Persistent URL http://hdl.handle.net/10536/DRO/DU:30073819

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 19 times in TR Web of Science
Scopus Citation Count Cited 20 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 233 Abstract Views, 3 File Downloads  -  Detailed Statistics
Created: Mon, 15 Jun 2015, 12:54:27 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.