Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China.

Peng, Daihui, Shen, Ting, Byrne, Linda, Zhang, Chen, Huang, Yueqi, Yu, Xin, Zhao, Jingping, McCabe, Marita, Mellor, David and Fang, Yiru 2015, Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China., Neuroscience bulletin, vol. 31, no. 1, pp. 22-30, doi: 10.1007/s12264-014-1487-3.

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Title Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China.
Author(s) Peng, Daihui
Shen, Ting
Byrne, LindaORCID iD for Byrne, Linda orcid.org/0000-0001-9055-0046
Zhang, Chen
Huang, Yueqi
Yu, Xin
Zhao, Jingping
McCabe, Marita
Mellor, DavidORCID iD for Mellor, David orcid.org/0000-0001-5007-5906
Fang, Yiru
Journal name Neuroscience bulletin
Volume number 31
Issue number 1
Start page 22
End page 30
Total pages 9
Publisher Springer
Place of publication Berlin, Germany
Publication date 2015-02
ISSN 1995-8218
Keyword(s) atypical features
bipolar
treatment
antidepressant
Summary In this study, we examined the point prevalence rate of atypical features in bipolar disorder, and estimated the potential impact of these features on treatment practices in China. Using the atypical features criteria of the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM-IV), we documented the atypical symptoms in 3 906 consecutive participants with bipolar disorder enrolled at 26 psychiatric services across China. We further assessed the association between atypical features and the treatment approaches, including the prescription of antidepressants. The overall point prevalence rate of atypical features was 9.1% among patients with various bipolar disorder subtypes. When the definition was broadened to include atypical features B, the overall rate increased to 11.8%. Interestingly, among patients with the mixed state and remission subtypes, there was a significant difference in the rates of antidepressant medication usage between patients who met and those who did not meet the criteria for atypical features B. These findings indicate a trend of using antidepressants for these two types of patients with atypical features. Further, for both mixed state and remission patients, treatment approaches were related to atypical features B. Our findings provide evidence to assist clinicians to readily recognize atypical features in bipolar subtypes and can propose treatments based on these diagnoses.
Language eng
DOI 10.1007/s12264-014-1487-3
Field of Research 170106 Health, Clinical and Counselling Psychology
1109 Neurosciences
1702 Cognitive Sciences
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, Springer
Persistent URL http://hdl.handle.net/10536/DRO/DU:30074644

Document type: Journal Article
Collection: School of Psychology
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