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Depressed mood, glycaemic control and functional capacity in overweight/obese men with and without type 2 diabetes

Levinger, Itamar, Selig, Steve, Jerums, George, Stewart, Andrew, Gaskin, Caderyn J. and Hare, David L. 2012, Depressed mood, glycaemic control and functional capacity in overweight/obese men with and without type 2 diabetes, Diabetology and metabolic syndrome, vol. 4, no. 1, pp. 1-7, doi: 10.1186/1758-5996-4-46.

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Title Depressed mood, glycaemic control and functional capacity in overweight/obese men with and without type 2 diabetes
Author(s) Levinger, Itamar
Selig, Steve
Jerums, George
Stewart, Andrew
Gaskin, Caderyn J.
Hare, David L.
Journal name Diabetology and metabolic syndrome
Volume number 4
Issue number 1
Article ID 46
Start page 1
End page 7
Total pages 7
Publisher BioMed Central
Place of publication London, Eng.
Publication date 2012-11-21
ISSN 1758-5996
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
Aerobic power
Cardiac Depression Scale
Depression
Glycaemic control
Type 2 diabetes
Summary OBJECTIVE: To determine whether there were differences in depressed mood between overweight/obese men with and without type 2 diabetes (T2DM) and to examine any associations between depressed mood, physical functioning, and glycaemic control in overweight/obese men with and without T2DM.
METHODS: Fifty seven overweight/obese men with (n = 19, age = 54.2 ± 7.4 yrs, BMI = 32.3 ± 6.7 kg⋅m-2) and without T2DM (n = 38, age = 51.1 ± 6.8 yrs, BMI = 29.9 ± 4.5kg⋅m-2, p > 0.05 between groups) participated. The men completed measures of depressed mood and health-related quality of life (HRQL) and underwent the following assessments: fasting blood lipids and glucose, HbA1c, anthropometric measurements, VO2peak, muscle strength, and physical function.
RESULTS: Compared to men without T2DM, men with T2DM had higher depressed mood (p = 0.05, η2 = 0.07), as well as lower perceived general health (p < .01, η2 = 0.24) and social functioning (p = .01, η2 = 0.10). Men with T2DM also had lower VO2peak (21.8 ± 5.3 versus 25.8 ± 5.4 ml⋅kg-1⋅min-1, p < .01, η2 = 0.11) and muscle strength (3.3 ± 0.8 versus 3.7 ± 0.7 kg⋅kg-1, p = 0.08, η2 = 0.06), as well as being slower to complete physical performance tasks (27.2 ± 5.2 versus 24.2 ± 2.8 sec, p < 0.01, η2 = 0.13). In those with T2DM, depressed mood was highly correlated with most HRQL subscales. For the combined cohort, depressed mood was correlated with fasting glucose (r = 0.31, p = 0.012) but not the functional measures.
CONCLUSIONS: Men with T2DM have higher levels of depressed mood compared to men without T2DM. Glycaemic control, but not functional capacities, is associated with depressed mood in the study cohort.
Language eng
DOI 10.1186/1758-5996-4-46
Field of Research 1103 Clinical Sciences
1101 Medical Biochemistry And Metabolomics
Socio Economic Objective 920504 Men's Health
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2012, Levinger et al.
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30075478

Document type: Journal Article
Collections: School of Medicine
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.