Phase asymmetry of heart rate variability signal

Karmakar, C.K., Khandoker, A.H. and Palaniswami, M. 2015, Phase asymmetry of heart rate variability signal, Physiological measurement, vol. 36, no. 2, pp. 303-314, doi: 10.1088/0967-3334/36/2/303.

Attached Files
Name Description MIMEType Size Downloads

Title Phase asymmetry of heart rate variability signal
Author(s) Karmakar, C.K.ORCID iD for Karmakar, C.K.
Khandoker, A.H.
Palaniswami, M.
Journal name Physiological measurement
Volume number 36
Issue number 2
Start page 303
End page 314
Total pages 12
Publisher IOP Publishing
Place of publication Bristol, Eng.
Publication date 2015-01-14
ISSN 1361-6579
Keyword(s) heart rate variability
heart rate asymmetry
asymmetry index
Poincaré plot
phase asymmetry
Summary Heart rate asymmetry (HRA) is considered as a physiological phenomenon in healthy subjects. In this article, we propose a novel HRA index, Slope Index (SI), to quantify phase asymmetry of heart rate variability (HRV) system. We assessed the performance of proposed index in comparison with conventional (Guzik's Index (GI) and Porta's Index (PI)) HRA indices. As illustrative examples, we used two case studies: (i) differentiate physiologic RR series from synthetic RR series; and (ii) discriminate arrhythmia subjects from Healthy using beat-to-beat heart rate time series. The results showed that SI is a superior parameter than GI and PI for both case studies with maximum ROC area of 0.84 and 0.82 respectively. In contrast, GI and PI had ROC areas {0.78, 0.61} and {0.50, 0.56} in two case studies respectively. We also performed surrogate analysis to show that phase asymmetry is caused by a physiologic phenomena rather than a random nature of the signal. In conclusion, quantification of phase asymmetry of HRV provides additional information on HRA, which might have a potential clinical use to discriminate pathological HRV in future.
Language eng
DOI 10.1088/0967-3334/36/2/303
Field of Research 090609 Signal Processing
090399 Biomedical Engineering not elsewhere classified
0903 Biomedical Engineering
1116 Medical Physiology
0906 Electrical And Electronic Engineering
Socio Economic Objective 970109 Expanding Knowledge in Engineering
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, IOP Publishing
Persistent URL

Connect to link resolver
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 10 times in TR Web of Science
Scopus Citation Count Cited 12 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 417 Abstract Views, 3 File Downloads  -  Detailed Statistics
Created: Thu, 31 Mar 2016, 09:43:53 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact