You are not logged in.

Design of endoperoxides with anti-Candida activity

Avery, Thomas D., Macreadie, Peter I., Greatrex, Ben W., Robinson, Tony V., Taylor, Dennis K. and Macreadie, Ian G. 2007, Design of endoperoxides with anti-Candida activity, Bioorganic & medicinal chemistry, vol. 15, no. 1, pp. 36-42, doi: 10.1016/j.bmc.2006.10.021.

Attached Files
Name Description MIMEType Size Downloads

Title Design of endoperoxides with anti-Candida activity
Author(s) Avery, Thomas D.
Macreadie, Peter I.ORCID iD for Macreadie, Peter I. orcid.org/0000-0001-7362-0882
Greatrex, Ben W.
Robinson, Tony V.
Taylor, Dennis K.
Macreadie, Ian G.
Journal name Bioorganic & medicinal chemistry
Volume number 15
Issue number 1
Start page 36
End page 42
Total pages 7
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2007-01-01
ISSN 0968-0896
Keyword(s) Antifungal
Artemisinin
Candida
Endoperoxide
Growth inhibition
Hemolytic activity
Summary Broad antifungal structure-activity relationships governing epoxy-endoperoxides 2 and 3 and their parent endoperoxides 1 are reported. Their inhibitory activity against Candida albicans in conjunction with hemolytic activity and/or growth inhibition of cultured mammalian cells are reported. This information provided guidance for the further development of endoperoxide and epoxy-endoperoxides as topical antifungal agents.
Language eng
DOI 10.1016/j.bmc.2006.10.021
Field of Research 030503 Organic Chemical Synthesis
Socio Economic Objective 860803 Human Pharmaceutical Treatments (e.g. Antibiotics)
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30076244

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 6 times in TR Web of Science
Scopus Citation Count Cited 7 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 82 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Fri, 21 Aug 2015, 15:04:34 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.