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Luminescent probes for the bioimaging of small anionic species in vitro and in vivo

Ashton, Trent D., Jolliffe, Katrina A. and Pfeffer, Frederick M. 2015, Luminescent probes for the bioimaging of small anionic species in vitro and in vivo, Chemical society reviews, vol. 44, no. 14, pp. 4547-4595, doi: 10.1039/c4cs00372a.

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Title Luminescent probes for the bioimaging of small anionic species in vitro and in vivo
Author(s) Ashton, Trent D.ORCID iD for Ashton, Trent D. orcid.org/0000-0002-6707-6064
Jolliffe, Katrina A.
Pfeffer, Frederick M.ORCID iD for Pfeffer, Frederick M. orcid.org/0000-0002-5441-6437
Journal name Chemical society reviews
Volume number 44
Issue number 14
Start page 4547
End page 4595
Total pages 49
Publisher Royal Society of Chemistry
Place of publication Cambridge, Eng.
Publication date 2015-07
ISSN 1460-4744
Keyword(s) Science & Technology
Physical Sciences
Chemistry, Multidisciplinary
Chemistry
RATIOMETRIC FLUORESCENT-PROBE
HYDROGEN-SULFIDE DETECTION
NEAR-INFRARED FLUORESCENCE
SYNTHETIC MEMBRANE TRANSPORTERS
PHOTOINDUCED ELECTRON-TRANSFER
INDICATOR-DISPLACEMENT ASSAYS
RECEPTOR CHEMISTRY HIGHLIGHTS
OPTICAL CHLORIDE SENSOR
FLUORIDE-ION DETECTION
DUAL-CHANNEL PROBE
Summary The ability to spatiotemporally identify the formation of specific anionic species, or track changes in their concentration inside living systems, is of critical importance in deciphering their exact biological roles and effects. The development of probes (also called bioimaging agents and intracellular sensors) to achieve this goal has become a rapidly growing branch of supramolecular chemistry. In this critical review the challenges specific to the task are identified and for a select range of small anions of environmental and biological relevance (fluoride, chloride, iodide, cyanide, pyrophosphate, bicarbonate, hydrosulphide, peroxynitrite, hypochlorite and hypobromite) a comprehensive overview of the currently available in vitro and in vivo probes is provided.
Language eng
DOI 10.1039/c4cs00372a
Field of Research 030302 Nanochemistry and Supramolecular Chemistry
030401 Biologically Active Molecules
03 Chemical Sciences
Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, Royal Society of Chemistry
Persistent URL http://hdl.handle.net/10536/DRO/DU:30076862

Document type: Journal Article
Collection: School of Life and Environmental Sciences
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Created: Fri, 27 Nov 2015, 09:59:46 EST

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