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DNA polymorphisms of the cholesteryl ester transfer protein (CETP) gene in Italian and Greek migrants to Australia

Mitchell, R.J., Earl, L., Bisucci, T., Gasiamis, H. and Williams, J. 1994, DNA polymorphisms of the cholesteryl ester transfer protein (CETP) gene in Italian and Greek migrants to Australia, Human heredity, vol. 44, no. 2, pp. 77-84.

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Title DNA polymorphisms of the cholesteryl ester transfer protein (CETP) gene in Italian and Greek migrants to Australia
Author(s) Mitchell, R.J.
Earl, L.
Bisucci, T.
Gasiamis, H.
Williams, J.ORCID iD for Williams, J. orcid.org/0000-0002-5633-1592
Journal name Human heredity
Volume number 44
Issue number 2
Start page 77
End page 84
Total pages 2
Publisher Karger
Place of publication Basel, Switzerland
Publication date 1994-03
ISSN 0001-5652
Keyword(s) Adult
Aged
Australia
Carrier Proteins
Cholesterol Ester Transfer Proteins
Deoxyribonucleases, Type II Site-Specific
Emigration and Immigration
European Continental Ancestry Group
Female
Glycoproteins
Greece
Humans
Italy
Male
Middle Aged
Polymorphism, Restriction Fragment Length
Summary The distribution of two common TaqI restriction fragment length polymorphisms (RFLPs) of the cholesteryl ester transfer protein (CETP) gene were determined in 271 Italian-born and 170 Greek-born migrants to Melbourne, Australia. A much smaller number were examined for the EcoNI RFLP of the same gene. Allele frequencies of the TaqI A RFLP exhibited the least variation in both ethnic groups, and no significant regional heterogeneity in allele or genotype frequencies of either TaqI RFLP was detected for Greece or Italy. There was no difference between Italians and Greeks for the TaqI A polymorphism and the variability at the B RFLP was of borderline significance. Comparisons with other Caucasian populations revealed that allele frequencies of all three CETP RFLPs are remarkably uniform within Caucasians, with the TaqI B polymorphism being the most variable.
Language eng
Field of Research 111799 Public Health and Health Services not elsewhere classified
0604 Genetics
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1994, Karger
Persistent URL http://hdl.handle.net/10536/DRO/DU:30077688

Document type: Journal Article
Collection: School of Health and Social Development
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