Movement-related potentials in high-functioning autism and Asperger's disorder Rinehart, Nicole J., Tonge, Bruce, Bradshaw, John L., Iansek, Robert, Enticott, Peter G. and Johnson, Katherine A. 2006, Movement-related potentials in high-functioning autism and Asperger's disorder, Developmental medicine and child neurology, vol. 48, no. 4, pp. 272-277, doi: 10.1017/S0012162206000594. Attached Files Name Description MIMEType Size Downloads Title Movement-related potentials in high-functioning autism and Asperger's disorder Author(s) Rinehart, Nicole J. orcid.org/0000-0001-6109-3958 Tonge, Bruce Bradshaw, John L. Iansek, Robert Enticott, Peter G. orcid.org/0000-0002-6638-951X Johnson, Katherine A. Journal name Developmental medicine and child neurology Volume number 48 Issue number 4 Start page 272 End page 277 Total pages 6 Publisher Wiley-Blackwell Place of publication Chichester, Eng. Publication date 2006-04 ISSN 0012-1622 Keyword(s) Adolescent Adult Asperger Syndrome Autistic Disorder Child Child, Preschool Diagnosis, Computer-Assisted Electroencephalography Evoked Potentials, Motor Female Humans Male Motor Cortex Movement Disorders Social Behavior Summary Autism and Asperger's disorder (AD) are neurodevelopmental conditions that affect cognitive and social-communicative function. Using a movement-related potential (MRP) paradigm, we investigated the clinical and neurobiological issue of 'disorder separateness' versus 'disorder variance' in autism and AD. This paradigm has been used to assess basal ganglia/supplementary motor functioning in Parkinson's disease. Three groups (high functioning autism [HFA]: 16 males, 1 female; mean age 12y 5mo [SD 4y 4mo]; AD: 11 males, 2 females; mean age 13y 5mo [SD 3y 8mo]; comparison group: 13 males, 8 females; mean age 13y 10mo [SD 3y 11mo]) completed a cued motor task during electroencephalogram recording of MRPs. The HFA group showed reduced peak amplitude at Cz, indicating less activity over the supplementary motor area during movement preparation. Although an overall significant between-group effect was found for early slope and peak amplitude, sub-analysis revealed that the group with AD did not differ significantly from either group. However, it is suggested that autism and AD may be dissociated on the basis of brain-behaviour correlations of IQ with specific neurobiological measures. The overlap between MRP traces for autism and Parkinson's disease suggests that the neurobiological wiring of motor functioning in autism may bypass the supplementary motor area/primary motor cortex pathway. Language eng DOI 10.1017/S0012162206000594 Field of Research 179999 Psychology and Cognitive Sciences not elsewhere classified 11 Medical And Health Sciences Socio Economic Objective 970117 Expanding Knowledge in Psychology and Cognitive Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2006, Wiley-Blackwell Persistent URL http://hdl.handle.net/10536/DRO/DU:30078048 Document type: Journal Article Collections: Faculty of Health School of Psychology Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 07 Sep 2015, 11:47:46 EST Tue, 08 Sep 2015, 05:02:45 EST Tue, 08 Sep 2015, 06:11:48 EST Sat, 15 Apr 2017, 02:38:24 EST Mon, 05 Jun 2017, 15:46:52 EST Mon, 05 Jun 2017, 15:48:47 EST Mon, 05 Jun 2017, 15:49:25 EST Tue, 20 Jun 2017, 11:35:09 EST Sat, 21 Oct 2017, 02:35:48 EST Filtered Full Citation counts:   Cited 34 times in TR Web of Science Cited 39 times in Scopus Search Google Scholar Access Statistics: 243 Abstract Views, 1 File Downloads  -  Detailed Statistics Created: Mon, 07 Sep 2015, 11:47:46 EST

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