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Identification and characterisation of a novel Interleukin-4 receptor antagonist for allergy treatment

Ahmed, Nayyar 2015, Identification and characterisation of a novel Interleukin-4 receptor antagonist for allergy treatment, PhD thesis, School of Life and Environmental Sciences, Deakin Univeristy.

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Title Identification and characterisation of a novel Interleukin-4 receptor antagonist for allergy treatment
Author Ahmed, Nayyar
Institution Deakin Univeristy
School School of Life and Environmental Sciences
Faculty Faculty of Science, Engineering and Built Environment
Degree type Research doctorate
Degree name PhD
Thesis advisor Barrow, Colin
Ackland, M. Leigh
Suphioglu, Cenk
Date submitted 2015-02
Keyword(s) allergy treatment
interleukin-4
peptide antagonist
ryegrass pollen data
fatty acids
resolvins
coenzyme Q10
Summary  The main focus of the PhD studies was the identification and characterization of a peptide antagonist which inhibited and/or down-regulated the binding of Interleukin-4 receptor to its cytokines IL-4 and IL-13 for allergy treatment. In addition, dietary components were tested for their ability to reduce inflammatory pathways of allergy, including fatty acids, resolvins and coenzyme Q10. Lastly, the Deakin AIRwatch project was undertaken which included the collection of ryegrass pollen data from 2012-2014 and its correlation with meteorological variables in regional Victoria.
Language eng
Field of Research 110701 Allergy
Socio Economic Objective 920108 Immune System and Allergy
Description of original xxvi, 212 pages : illustrations, tables, graphs, some coloured
Dewey Decimal Classification 616.9706
Copyright notice ┬ęThe Author. All Rights Reserved
Free to Read? Yes
Free to Read Start Date 2016-03-08
Persistent URL http://hdl.handle.net/10536/DRO/DU:30079029

Document type: Thesis
Collections: Higher degree theses (full text)
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Created: Fri, 16 Oct 2015, 14:13:26 EST by Kate Percival

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.