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PTEX characterisation and its role in Plasmodium virulence and survival

Matthews, Kathryn 2015, PTEX characterisation and its role in Plasmodium virulence and survival, PhD thesis, School of Medicine, Deakin Univeristy.

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Title PTEX characterisation and its role in Plasmodium virulence and survival
Author Matthews, Kathryn
Institution Deakin Univeristy
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name PhD
Thesis advisor De Koning-Ward, TaniaORCID iD for De Koning-Ward, Tania orcid.org/0000-0001-5810-8063
Ming Kalanon
Date submitted 2015-03
Keyword(s) malaria
plasmodium parasites
erythrocytes
putative export machinery (PTEX)
parasite-exported proteins
drug targeting
Summary  Malaria parasites remodel erythrocytes for their survival. They passage proteins into the host cell via an export machinery known as PTEX. For the first time, this study shows that different types of parasite-exported proteins use PTEX. Importantly, new drugs can be developed which target PTEX components to eliminate an infection.
Language eng
Field of Research 060502 Infectious Agents
060108 Protein Trafficking
Socio Economic Objective 960399 Climate and Climate Change not elsewhere classified
Description of original xvi, 172 pages : illustrations, tables, graphs
Copyright notice ┬ęThe Author. All Rights Reserved
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30079075

Document type: Thesis
Collections: Higher degree theses (full text)
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Created: Thu, 22 Oct 2015, 12:33:40 EST by Kate Percival

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.