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Dissecting ADAMTS proteoglycanase biology in development and disease

Dancevic, Carolyn 2015, Dissecting ADAMTS proteoglycanase biology in development and disease, Ph.D. thesis, School of Medicine, Deakin University.

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Title Dissecting ADAMTS proteoglycanase biology in development and disease
Author Dancevic, Carolyn
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name Ph.D.
Thesis advisor Ward, Alister C.ORCID iD for Ward, Alister C. orcid.org/0000-0001-7945-7975
McCulloch, Daniel
Gibert, Yann
Date submitted 2015-08
Keyword(s) ADAMTS
proteins
arthritis
Summary  This research was focused upon members of the ADAMTS family of 'proteinases', proteins that have enzymatic activity. Their dysregulation can cause developmental defects and disease. This thesis describes the expression and regulation of ADAMTS15, as well as new developmental functions and inhibition of ADAMTS5 in arthritis.
Language eng
Field of Research 060803 Animal Developmental and Reproductive Biology
110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics)
110322 Rheumatology and Arthritis
Socio Economic Objective 920116 Skeletal System and Disorders (incl. Arthritis)
Description of original xiii, 165 pages : illustrations, some coloured, tables, graphs
Dewey Decimal Classification 572.6
Copyright notice ┬ęThe author
Persistent URL http://hdl.handle.net/10536/DRO/DU:30079439

Document type: Thesis
Collection: Higher degree theses (citation only)
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Created: Wed, 11 Nov 2015, 15:09:09 EST by Kate Percival

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