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Economic evaluation of a psychological intervention for high distress cancer patients and carers: costs and quality-adjusted life years

Chatterton, Mary Lou, Chambers, Suzanne, Occhipinti, Stefano, Girgis, Afaf, Dunn, Jeffrey, Carter, Rob, Shih, Sophy and Mihalopoulos, Cathrine 2016, Economic evaluation of a psychological intervention for high distress cancer patients and carers: costs and quality-adjusted life years, Psycho-oncology, vol. 25, no. 7, pp. 857-864, doi: 10.1002/pon.4020.

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Title Economic evaluation of a psychological intervention for high distress cancer patients and carers: costs and quality-adjusted life years
Author(s) Chatterton, Mary Lou
Chambers, Suzanne
Occhipinti, Stefano
Girgis, Afaf
Dunn, Jeffrey
Carter, Rob
Shih, SophyORCID iD for Shih, Sophy orcid.org/0000-0003-0049-2888
Mihalopoulos, CathrineORCID iD for Mihalopoulos, Cathrine orcid.org/0000-0002-7127-9462
Journal name Psycho-oncology
Volume number 25
Issue number 7
Start page 857
End page 864
Total pages 8
Publisher Wiley
Place of publication Chichester, Eng.
Publication date 2016-07
ISSN 1057-9249
1099-1611
Summary OBJECTIVE: This study compared the cost-effectiveness of a psychologist-led, individualised cognitive behavioural intervention (PI) to a nurse-led, minimal contact self-management condition for highly distressed cancer patients and carers.

METHODS: This was an economic evaluation conducted alongside a randomised trial of highly distressed adult cancer patients and carers calling cancer helplines. Services used by participants were measured using a resource use questionnaire, and quality-adjusted life years were measured using the assessment of quality of life - eight-dimension - instrument collected through a computer-assisted telephone interview. The base case analysis stratified participants based on the baseline score on the Brief Symptom Inventory. Incremental cost-effectiveness ratio confidence intervals were calculated with a nonparametric bootstrap to reflect sampling uncertainty. The results were subjected to sensitivity analysis by varying unit costs for resource use and the method for handling missing data.

RESULTS: No significant differences were found in overall total costs or quality-adjusted life years (QALYs) between intervention groups. Bootstrapped data suggest the PI had a higher probability of lower cost and greater QALYs for both carers and patients with high distress at baseline. For patients with low levels of distress at baseline, the PI had a higher probability of greater QALYs but at additional cost. Sensitivity analysis showed the results were robust.

CONCLUSIONS: The PI may be cost-effective compared with the nurse-led, minimal contact self-management condition for highly distressed cancer patients and carers. More intensive psychological intervention for patients with greater levels of distress appears warranted.
Language eng
DOI 10.1002/pon.4020
Field of Research 1112 Oncology And Carcinogenesis
1701 Psychology
1103 Clinical Sciences
140208 Health Economics
Socio Economic Objective 920102 Cancer and Related Disorders
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, John Wiley & Sons
Persistent URL http://hdl.handle.net/10536/DRO/DU:30079659

Document type: Journal Article
Collection: Population Health
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