Cancer stem cell targeted therapy: progress amid controversies Wang, Tao, Shigdar, Sarah, Gantier, Michael P., Hou, Yingchun, Wang, Li, Li, Yong, Al Shamaileh, Hadi, Yin, Wang, Zhou, Shu Feng, Zhao, Xinhan and Duan, Wei 2015, Cancer stem cell targeted therapy: progress amid controversies, Oncotarget, vol. 6, no. 42, pp. 44191-44206, doi: 10.18632/oncotarget.6176. Attached Files Name Description MIMEType Size Downloads wang-cancerstem-2015.pdf Published version application/pdf 3.45MB 13 Title Cancer stem cell targeted therapy: progress amid controversies Author(s) Wang, Tao Shigdar, Sarah orcid.org/0000-0001-8084-8447 Gantier, Michael P. Hou, Yingchun Wang, Li Li, Yong Al Shamaileh, Hadi Yin, Wang orcid.org/0000-0002-5665-3559 Zhou, Shu Feng Zhao, Xinhan Duan, Wei orcid.org/0000-0001-5782-9184 Journal name Oncotarget Volume number 6 Issue number 42 Start page 44191 End page 44206 Total pages 16 Publisher Impact Journals Place of publication Albany, N.Y. Publication date 2015-10-19 ISSN 1949-2553 Keyword(s) anti-cancer treatment cancer cancer stem cell cancer stem cell marker cancer stem cell model Summary Although cancer stem cells have been well characterized in numerous malignancies, the fundamental characteristics of this group of cells, however, have been challenged by some recent observations: cancer stem cells may not necessary to be rare within tumors; cancer stem cells and non-cancer stem cells may undergo reversible phenotypic changes; and the cancer stem cells phenotype can vary substantially between patients. Here the current status and progresses of cancer stem cells theory is illustrated and via providing a panoramic view of cancer therapy, we addressed the recent controversies regarding the feasibility of cancer stem cells targeted anti-cancer therapy. Language eng DOI 10.18632/oncotarget.6176 Field of Research 111204 Cancer Therapy (excl Chemotherapy and Radiation Therapy) Socio Economic Objective 920102 Cancer and Related Disorders HERDC Research category C1 Refereed article in a scholarly journal ERA Research output type C Journal article Copyright notice ©2015, The Authors Free to Read? Yes Use Rights Persistent URL http://hdl.handle.net/10536/DRO/DU:30080436 Document type: Journal Article Collections: School of Medicine Open Access Collection Related Links Link Description Connect to published version Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Wed, 06 Jan 2016, 08:18:44 EST Wed, 06 Jan 2016, 08:19:16 EST Thu, 07 Jan 2016, 04:00:30 EST Fri, 15 Jan 2016, 05:08:17 EST Tue, 05 Jul 2016, 15:16:54 EST Tue, 05 Jul 2016, 15:26:12 EST Fri, 08 Jul 2016, 11:45:05 EST Fri, 08 Jul 2016, 11:51:45 EST Wed, 12 Oct 2016, 14:35:15 EST Wed, 09 Nov 2016, 11:33:39 EST Fri, 10 Feb 2017, 12:52:10 EST Wed, 01 Mar 2017, 07:38:12 EST Fri, 03 Mar 2017, 13:21:32 EST Filtered Full Citation counts:   Cited 22 times in TR Web of Science Cited 28 times in Scopus Search Google Scholar Access Statistics: 170 Abstract Views, 14 File Downloads  -  Detailed Statistics Created: Wed, 06 Jan 2016, 08:19:16 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.