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Application of Aptamers in Histopathology.

Shigdar, Sarah, Lv, Li, Wang, Lifen and Duan, Wei 2016, Application of Aptamers in Histopathology.Nucleic acid aptamers : selection, characterization and application, Humana Press, New York, N.Y., pp.191-196, doi: 10.1007/978-1-4939-3197-2_16.

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Title Application of Aptamers in Histopathology.
Author(s) Shigdar, Sarah
Lv, Li
Wang, Lifen
Duan, Wei
Title of book Nucleic acid aptamers : selection, characterization and application
Publication date 2016
Series Methods in molecular biology
Chapter number 16
Total chapters 19
Start page 191
End page 196
Total pages 6
Publisher Humana Press
Place of Publication New York, N.Y.
Keyword(s) Aptamers
Chemical antibodies
Chromogenic staining
Diagnostics
Histology
Immunohistochemistry
Paraffin-embedded tissues
Pathology
Summary Aptamers are proving to be exceedingly effective in a number of applications. Given the disadvantages of antibodies, such as batch-to-batch variation and cross-reactivity, aptamers have the potential to revolutionize the field of histopathology due to their high specificity and the ease of their synthesis and modification. Here, we describe a chromogenic staining method for paraffin-embedded tissue sections with FITC-labeled aptamers.
ISBN 9781493931965
ISSN 1940-6029
Language eng
DOI 10.1007/978-1-4939-3197-2_16
Field of Research 060199 Biochemistry and Cell Biology not elsewhere classified
0601 Biochemistry And Cell Biology
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category B1 Book chapter
ERA Research output type B Book chapter
Copyright notice ©2016, Humana Press
Persistent URL http://hdl.handle.net/10536/DRO/DU:30080595

Document type: Book Chapter
Collection: School of Medicine
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