Selection on mitochondrial variants occurs between and within individuals in an expanding invasion

Rollins, Lee A., Woolnough, Andrew P., Fanson, Benjamin G., Cummins, Michelle L., Crowley, Tamsyn, Wilton, Alan W., Sinclair, Ron, Butler, Ashleigh and Sherwin, William B. 2016, Selection on mitochondrial variants occurs between and within individuals in an expanding invasion, Molecular biology and evolution, vol. 33, no. 4, pp. 995-1007, doi: 10.1093/molbev/msv343.

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Title Selection on mitochondrial variants occurs between and within individuals in an expanding invasion
Author(s) Rollins, Lee A.ORCID iD for Rollins, Lee A.
Woolnough, Andrew P.
Fanson, Benjamin G.
Cummins, Michelle L.
Crowley, TamsynORCID iD for Crowley, Tamsyn
Wilton, Alan W.
Sinclair, Ron
Butler, Ashleigh
Sherwin, William B.
Journal name Molecular biology and evolution
Volume number 33
Issue number 4
Start page 995
End page 1007
Total pages 13
Publisher Oxford University Press
Place of publication Oxford, Eng.
Publication date 2016-04
ISSN 1537-1719
Keyword(s) heteroplasmy
invasive species
mitochondrial DNA copy number
rapid evolution
Summary Mitochondria are critical for life, yet their underlying evolutionary biology is poorly understood. In particular, little is known about interaction between two levels of evolution: between individuals and within individuals (competition between cells, mitochondria or mitochondrial DNA molecules). Rapid evolution is suspected to occur frequently in mitochondrial DNA, whose maternal inheritance predisposes advantageous mutations to sweep rapidly though populations. Rapid evolution is also predicted in response to changed selection regimes after species invasion or removal of pathogens or competitors. Here, using empirical and simulated data from a model invasive bird species, we provide the first demonstration of rapid selection on the mitochondrial genome within individuals in the wild. Further, we show differences in mitochondrial DNA copy number associated with competing genetic variants, which may provide a mechanism for selection. We provide evidence for three rarely documented phenomena: selection associated with mitochondrial DNA abundance, selection on the mitochondrial control region, and contemporary selection during invasion.
Language eng
DOI 10.1093/molbev/msv343
Field of Research 060411 Population, Ecological and Evolutionary Genetics
0604 Genetics
0603 Evolutionary Biology
0601 Biochemistry And Cell Biology
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Grant ID LP0455776
Copyright notice ©2016, The Authors
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