Male sex and pre-existing diabetes are independent risk factors for stillbirth Engel, Patricia J., Smith, Roger, Brinsmead, Maxwell W., Bowe, Stephen J. and Clifton, Vicki L. 2008, Male sex and pre-existing diabetes are independent risk factors for stillbirth, Australian and New Zealand journal of obstetrics and gynaecology, vol. 48, no. 4, pp. 375-383, doi: 10.1111/j.1479-828X.2008.00863.x. Attached Files Name Description MIMEType Size Downloads Title Male sex and pre-existing diabetes are independent risk factors for stillbirth Author(s) Engel, Patricia J. Smith, Roger Brinsmead, Maxwell W. Bowe, Stephen J. orcid.org/0000-0003-3813-842X Clifton, Vicki L. Journal name Australian and New Zealand journal of obstetrics and gynaecology Volume number 48 Issue number 4 Start page 375 End page 383 Total pages 9 Publisher Wiley Place of publication London, Eng. Publication date 2008-08 ISSN 1479-828X Summary AIM: To determine whether the risk of stillbirth is associated with male fetal sex, fetal growth and maternal factors in an Australian population. METHODS: A retrospective secondary data analysis of 16 445 singleton births was performed using a tertiary referral centre obstetric database (1995-1999). Univariate and multiple logistic regression analyses were performed. RESULTS: Stillbirth complicated 1% of the pregnancies in the study population, and 59% of stillbirths were associated with a male fetus. Significant characteristics associated with stillbirth were intrauterine growth restriction (IUGR), birth defects, gestational age, Aboriginal ethnicity, previous stillbirth, parity greater than three and placental abruption. Male stillbirths were more likely to occur at a later gestation (median gestation 30.5 weeks, range 20-43 weeks) compared to females (median 25 weeks, range 20-40 weeks), P = 0.01. Sixty per cent of IUGR fetuses were female (P < 0.001). Male sex (odds ratio (OR) 1.5, confidence interval (CI) 1.01, 2.17, P = 0.04) and maternal type 1 diabetes (OR 4.7, CI 1.58, 14.19, P = 0.006) were independently associated with stillbirth. CONCLUSION: Male fetal sex and pre-existing diabetes are independent risk factors for stillbirth. Diabetes remains a significant risk for stillbirth even with contemporary monitoring and clinical management. Those diabetic pregnancies where the fetus is male require appropriate monitoring and timely interventions to achieve an optimal outcome. Language eng DOI 10.1111/j.1479-828X.2008.00863.x Field of Research 111499 Paediatrics and Reproductive Medicine not elsewhere classified Socio Economic Objective 920114 Reproductive System and Disorders HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2008, The Authors Persistent URL http://hdl.handle.net/10536/DRO/DU:30081014 Document type: Journal Article Collections: Faculty of Health PVC's Office - Health Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 29 Jan 2016, 09:37:43 EST Sat, 30 Jan 2016, 04:01:11 EST Mon, 01 Feb 2016, 07:43:34 EST Thu, 18 Feb 2016, 08:45:25 EST Mon, 22 Feb 2016, 13:07:17 EST Mon, 22 Feb 2016, 13:09:19 EST Filtered Full Citation counts:   Cited 37 times in TR Web of Science Cited 37 times in Scopus Search Google Scholar Access Statistics: 367 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Thu, 18 Feb 2016, 08:45:25 EST

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