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Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

Pipingas, Andrew, Sinclair, Andrew, Croft, Kevin D., Januszewski, Andrzej S., Jenkins, Alicia J., Mori, Trevor A., Cockerell, Robyn, Grima, Natalie A., Stough, Con, Scholey, Andrew, Myers, Stephen P., Sali, Avni and Pase, Matthew P. 2015, Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial, Journal of functional foods, vol. 19, no. Part B, pp. 949-957, doi: 10.1016/j.jff.2014.10.028.

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Title Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial
Author(s) Pipingas, Andrew
Sinclair, Andrew
Croft, Kevin D.
Januszewski, Andrzej S.
Jenkins, Alicia J.
Mori, Trevor A.
Cockerell, Robyn
Grima, Natalie A.
Stough, Con
Scholey, Andrew
Myers, Stephen P.
Sali, Avni
Pase, Matthew P.
Journal name Journal of functional foods
Volume number 19
Issue number Part B
Start page 949
End page 957
Total pages 9
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2015-12
ISSN 1756-4646
Keyword(s) fish oil
PUFA
multivitamins
inflammation
oxidative stress
F-2-isoprostanes
Summary The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.
Language eng
DOI 10.1016/j.jff.2014.10.028
Field of Research 1111 Nutrition And Dietetics
0908 Food Sciences
Socio Economic Objective 920411 Nutrition
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30081317

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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