Quantifying the proportion of deaths due to body mass index- and waist circumference-defined obesity

Tanamas, Stephanie K., Ng, Winda L., Backholer, Kathryn, Hodge, Allison, Zimmet, Paul Z. and Peeters, Anna 2016, Quantifying the proportion of deaths due to body mass index- and waist circumference-defined obesity, Obesity, vol. 24, no. 3, pp. 735-742, doi: 10.1002/oby.21386.

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Title Quantifying the proportion of deaths due to body mass index- and waist circumference-defined obesity
Author(s) Tanamas, Stephanie K.
Ng, Winda L.
Backholer, KathrynORCID iD for Backholer, Kathryn orcid.org/0000-0002-3323-575X
Hodge, Allison
Zimmet, Paul Z.
Peeters, AnnaORCID iD for Peeters, Anna orcid.org/0000-0003-4340-9132
Journal name Obesity
Volume number 24
Issue number 3
Start page 735
End page 742
Total pages 8
Publisher Wiley-Blackwell
Place of publication Chichester, Eng.
Publication date 2016-03
ISSN 1930-739X
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
Nutrition & Dietetics
Summary OBJECTIVE: To determine the risk of mortality associated with and quantify the deaths attributable to combinations of body mass index (BMI) and waist circumference (WC). METHODS: This study included 41,439 participants. For the hazard ratio (HR) calculation, adiposity categories were defined as: BMI(N) /WC(N) , BMI(N) /WC(O) , BMI(O) /WC(N) , and BMI(O) /WC(O) (N = non-obese, O = obese). For the population attributable fraction analysis, obesity was classified as: (i) obese by BMI and/or WC; (ii) obese by BMI; and (iii) obese by WC. Mortality data was complete to the end of 2012. RESULTS: The prevalence of BMI(N) /WC(N) , BMI(N) /WC(O) , BMI(O) /WC(N) , and BMI(O) /WC(O) was 73%, 6%, 6%, and 15%, respectively. There was an increased risk of all-cause and cardiovascular disease (CVD) mortality in those with BMI(N) /WC(O) (HR (95% CI) 1.2 (1.2, 1.3) and 1.3 (1.1, 1.6)) and BMI(O) /WC(O) (1.3 (1.3, 1.4) and 1.7 (1.5, 1.9)) compared to those with BMI(N) /WC(N) . The estimated proportion of all-cause and CVD mortality attributable to obesity defined using WC or using BMI and/or WC was higher compared to obesity defined using BMI. CONCLUSIONS: Current population obesity monitoring misses those with BMI(N) /WC(O) who are at increased risk of mortality. By targeting reductions in population WC, the potential exists to prevent more deaths in the population than if we continue to target reductions in BMI alone.
Language eng
DOI 10.1002/oby.21386
Field of Research 111706 Epidemiology
Socio Economic Objective 920411 Nutrition
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Obesity Society
Persistent URL http://hdl.handle.net/10536/DRO/DU:30081567

Document type: Journal Article
Collections: Faculty of Health
School of Health and Social Development
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