Obesity in adulthood and its consequences for life expectancy: a life-table analysis

Peeters, Anna, Barendregt, Jan J., Willekens, Frans, Mackenbach, Johan P., Al Mamun, Abdullah and Bonneux, Luc 2003, Obesity in adulthood and its consequences for life expectancy: a life-table analysis, Annals of internal medicine, vol. 138, no. 1, pp. 24-32, doi: 10.7326/0003-4819-138-1-200301070-00008.

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Title Obesity in adulthood and its consequences for life expectancy: a life-table analysis
Author(s) Peeters, AnnaORCID iD for Peeters, Anna orcid.org/0000-0003-4340-9132
Barendregt, Jan J.
Willekens, Frans
Mackenbach, Johan P.
Al Mamun, Abdullah
Bonneux, Luc
Journal name Annals of internal medicine
Volume number 138
Issue number 1
Start page 24
End page 32
Total pages 9
Publisher American College of Physicians
Place of publication Philadelphia, Pa.
Publication date 2003-01-07
ISSN 1539-3704
Keyword(s) NEDCOM, the Netherlands Epidemiology and Demography Compression of Morbidity Research Group
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
Summary BACKGROUND: Overweight and obesity in adulthood are linked to an increased risk for death and disease. Their potential effect on life expectancy and premature death has not yet been described. OBJECTIVE: To analyze reductions in life expectancy and increases in premature death associated with overweight and obesity at 40 years of age. DESIGN: Prospective cohort study. SETTING: The Framingham Heart Study with follow-up from 1948 to 1990. PARTICIPANTS: 3457 Framingham Heart Study participants who were 30 to 49 years of age at baseline. MEASUREMENTS: Mortality rates specific for age and body mass index group (normal weight, overweight, or obese at baseline) were derived within sex and smoking status strata. Life expectancy and the probability of death before 70 years of age were analyzed by using life tables. RESULTS: Large decreases in life expectancy were associated with overweight and obesity. Forty-year-old female nonsmokers lost 3.3 years and 40-year-old male nonsmokers lost 3.1 years of life expectancy because of overweight. Forty-year-old female nonsmokers lost 7.1 years and 40-year-old male nonsmokers lost 5.8 years because of obesity. Obese female smokers lost 7.2 years and obese male smokers lost 6.7 years of life expectancy compared with normal-weight smokers. Obese female smokers lost 13.3 years and obese male smokers lost 13.7 years compared with normal-weight nonsmokers. Body mass index at ages 30 to 49 years predicted mortality after ages 50 to 69 years, even after adjustment for body mass index at age 50 to 69 years. CONCLUSIONS: Obesity and overweight in adulthood are associated with large decreases in life expectancy and increases in early mortality. These decreases are similar to those seen with smoking. Obesity in adulthood is a powerful predictor of death at older ages. Because of the increasing prevalence of obesity, more efficient prevention and treatment should become high priorities in public health.
Language eng
DOI 10.7326/0003-4819-138-1-200301070-00008
Field of Research 11 Medical And Health Sciences
111799 Public Health and Health Services not elsewhere classified
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2003, American College of Physicians
Persistent URL http://hdl.handle.net/10536/DRO/DU:30081569

Document type: Journal Article
Collections: Faculty of Health
School of Health and Social Development
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