How do the Australian guidelines for lipid-lowering drugs perform in practice? Cardiovascular disease risk in the AusDiab Study, 1999-2000

Chen, Lei, Rogers, Sophie L., Colagiuri, Stephen, Cadilhac, Dominique A., Mathew, Timothy H., Boyden, Andrew N., Peeters, Anna, Magliano, Dianna J., Shaw, Jonathan E., Zimmet, Paul Z. and Tonkin, Andrew M. 2008, How do the Australian guidelines for lipid-lowering drugs perform in practice? Cardiovascular disease risk in the AusDiab Study, 1999-2000, Medical journal of Australia, vol. 189, no. 6, pp. 319-322.

Attached Files
Name Description MIMEType Size Downloads

Title How do the Australian guidelines for lipid-lowering drugs perform in practice? Cardiovascular disease risk in the AusDiab Study, 1999-2000
Author(s) Chen, Lei
Rogers, Sophie L.
Colagiuri, Stephen
Cadilhac, Dominique A.
Mathew, Timothy H.
Boyden, Andrew N.
Peeters, AnnaORCID iD for Peeters, Anna
Magliano, Dianna J.
Shaw, Jonathan E.
Zimmet, Paul Z.
Tonkin, Andrew M.
Journal name Medical journal of Australia
Volume number 189
Issue number 6
Start page 319
End page 322
Total pages 4
Publisher Australasian Medical Publishing Company
Place of publication Strawberry Hills, N.S.W
Publication date 2008-09-15
ISSN 0025-729X
Keyword(s) National Vascular Disease Prevention Alliance
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
Summary OBJECTIVE: To determine how well the current Pharmaceutical Benefits Scheme (PBS) eligibility criteria for subsidy of lipid-lowering drugs compare with current national guidelines for determining the population at high risk of developing cardiovascular disease (CVD). DESIGN AND PARTICIPANTS: Analyses of the population-based, cross-sectional Australian Diabetes, Obesity and Lifestyle (AusDiab) study, conducted in 1999-2000. The 1991 Framingham risk prediction equation was used to compute 5-year risk of developing first-time CVD in 8286 participants aged 30-74 years with neither CVD nor diabetes. Based on the National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand guidelines, people with either 5-year CVD risk > or = 15% or with 5-year CVD risk of 10%-< 15% and the metabolic syndrome were defined as having estimated high absolute CVD risk. MAIN OUTCOME MEASURES: 5-year CVD risk; estimated population with high CVD risk. RESULTS: Among participants without prevalent CVD or diabetes, 7.9% of men and 1.5% of women had a 5-year CVD risk > or = 15%. Of the estimated residential Australian population in 2000 aged 30-74 years without CVD or diabetes, 717 000 people were considered to be at high absolute CVD risk. Among the high-risk AusDiab participants without CVD or diabetes, only 16.9% of men and 15.4% of women were being treated with lipid-lowering drugs. Of the 9.6% of participants free of CVD and diabetes who were untreated but eligible for subsidy under PBS criteria, only 27.4% had an estimated high absolute CVD risk. CONCLUSION: Strategies for CVD prevention using lipid-lowering medications can be improved by adoption of the absolute-risk approach.
Language eng
Field of Research 1117 Public Health And Health Services
1103 Clinical Sciences
111799 Public Health and Health Services not elsewhere classified
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2008, Australasian Medical Publishing Company
Persistent URL

Document type: Journal Article
Collections: Faculty of Health
School of Health and Social Development
Connect to link resolver
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 19 times in TR Web of Science
Scopus Citation Count Cited 19 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 416 Abstract Views, 1 File Downloads  -  Detailed Statistics
Created: Tue, 23 Feb 2016, 14:10:20 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact