Processing and characterization of srTiO₃-TiO₂ nanoparticle-nanotube heterostructures on titanium for biomedical applications

Wang, Yu, Zhang, Dongmei, Wen, Cuie and Li, Yuncang 2015, Processing and characterization of srTiO₃-TiO₂ nanoparticle-nanotube heterostructures on titanium for biomedical applications, ACS applied materials & interfaces, vol. 7, no. 29, pp. 16018-16026, doi: 10.1021/acsami.5b04304.

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Title Processing and characterization of srTiO₃-TiO₂ nanoparticle-nanotube heterostructures on titanium for biomedical applications
Author(s) Wang, Yu
Zhang, Dongmei
Wen, Cuie
Li, Yuncang
Journal name ACS applied materials & interfaces
Volume number 7
Issue number 29
Start page 16018
End page 16026
Total pages 9
Publisher American Chemical Society
Place of publication Washington, D.C.
Publication date 2015-07-02
ISSN 1944-8252
Keyword(s) SaOS2 cell
SrTiO3−TiO2 nanoparticle−nanotube heterostructure
TiO2 nanotube
Surface energy
Science & Technology
Nanoscience & Nanotechnology
Materials Science, Multidisciplinary
Science & Technology - Other Topics
Materials Science
SeTiO3-TiO2 nanoparticle-nanotube heterostructure
Summary Surface properties such as physicochemical characteristics and topographical parameters of biomaterials, essentially determining the interaction between the biological cells and the biomaterial, are important considerations in the design of implant materials. In this study, a layer of SrTiO3-TiO2 nanoparticle-nanotube heterostructures on titanium has been fabricated via anodization combined with a hydrothermal process. Titanium was anodized to create a layer of titania (TiO2) nanotubes (TNTs), which was then decorated with a layer of SrTiO3 nanoparticles via hydrothermal processing. SrTiO3-TiO2 heterostructures with high and low volume fraction of SrTiO3 nanoparticle (denoted by 6.3-Sr/TNTs and 1.4-Sr/TNTs) were achieved by using a hydrothermal processing time of 12 and 3 h, respectively. The in vitro biocompatibility of the SrTiO3-TiO2 heterostructures was assessed by using osteoblast cells (SaOS2). Our results indicated that the SrTiO3-TiO2 heterostructures with different volume fractions of SrTiO3 nanoparticles exhibited different Sr ion release in cell culture media and different surface energies. An appropriate volume fraction of SrTiO3 in the heterostructures stimulated the secretion of cell filopodia, leading to enhanced biocompatibility in terms of cell attachment, anchoring, and proliferation on the heterostructure surface.
Language eng
DOI 10.1021/acsami.5b04304
Field of Research 091205 Functional Materials
0904 Chemical Engineering
0303 Macromolecular And Materials Chemistry
0306 Physical Chemistry (Incl. Structural)
Socio Economic Objective 870302 Metals (e.g. Composites
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, American Chemical Society
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