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Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries

Celis-Morales, Carlos, Livingstone, Katherine M., Marsaux, Cyril F. M., Forster, Hannah, O'Donovan, Clare B., Woolhead, Clara, Macready, Anna L., Fallaize, Rosalind, Navas-Carretero, Santiago, San-Cristobal, Rodrigo, Kolossa, Silvia, Hartwig, Kai, Tsirigoti, Lydia, Lambrinou, Christina P., Moschonis, George, Godlewska, Magdalena, Surwiłło, Agnieszka, Grimaldi, Keith, Bouwman, Jildau, Daly, E. J., Akujobi, Victor, O'Riordan, Rick, Hoonhout, Jettie, Claassen, Arjan, Hoeller, Ulrich, Gundersen, Thomas E., Kaland, Siv E., Matthews, John N. S., Manios, Yannis, Traczyk, Iwona, Drevon, Christian A., Gibney, Eileen R., Brennan, Lorraine, Walsh, Marianne C., Lovegrove, Julie A., Martinez, J. Alfredo, Saris, Wim H. M., Daniel, Hannelore, Gibney, Mike and Mathers, John C. 2015, Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries, Genes & nutrition, vol. 10, no. 1, pp. 450, doi: 10.1007/s12263-014-0450-2.

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Title Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries
Author(s) Celis-Morales, Carlos
Livingstone, Katherine M.ORCID iD for Livingstone, Katherine M. orcid.org/0000-0002-9682-7541
Marsaux, Cyril F. M.
Forster, Hannah
O'Donovan, Clare B.
Woolhead, Clara
Macready, Anna L.
Fallaize, Rosalind
Navas-Carretero, Santiago
San-Cristobal, Rodrigo
Kolossa, Silvia
Hartwig, Kai
Tsirigoti, Lydia
Lambrinou, Christina P.
Moschonis, George
Godlewska, Magdalena
Surwiłło, Agnieszka
Grimaldi, Keith
Bouwman, Jildau
Daly, E. J.
Akujobi, Victor
O'Riordan, Rick
Hoonhout, Jettie
Claassen, Arjan
Hoeller, Ulrich
Gundersen, Thomas E.
Kaland, Siv E.
Matthews, John N. S.
Manios, Yannis
Traczyk, Iwona
Drevon, Christian A.
Gibney, Eileen R.
Brennan, Lorraine
Walsh, Marianne C.
Lovegrove, Julie A.
Martinez, J. Alfredo
Saris, Wim H. M.
Daniel, Hannelore
Gibney, Mike
Mathers, John C.
Journal name Genes & nutrition
Volume number 10
Issue number 1
Start page 450
Total pages 13
Publisher Springer
Place of publication Berlin, Germany
Publication date 2015-01
ISSN 1555-8932
Keyword(s) personalised nutrition
web-based
phenotype
genotype
randomised controlled trial
Summary Improving lifestyle behaviours has considerable potential for reducing the global burden of non-communicable diseases, promoting better health across the life-course and increasing well-being. However, realising this potential will require the development, testing and implementation of much more effective behaviour change interventions than are used conventionally. Therefore, the aim of this study was to conduct a multi-centre, web-based, proof-of-principle study of personalised nutrition (PN) to determine whether providing more personalised dietary advice leads to greater improvements in eating patterns and health outcomes compared to conventional population-based advice. A total of 5,562 volunteers were screened across seven European countries; the first 1,607 participants who fulfilled the inclusion criteria were recruited into the trial. Participants were randomly assigned to one of the following intervention groups for a 6-month period: Level 0-control group-receiving conventional, non-PN advice; Level 1-receiving PN advice based on dietary intake data alone; Level 2-receiving PN advice based on dietary intake and phenotypic data; and Level 3-receiving PN advice based on dietary intake, phenotypic and genotypic data. A total of 1,607 participants had a mean age of 39.8 years (ranging from 18 to 79 years). Of these participants, 60.9 % were women and 96.7 % were from white-European background. The mean BMI for all randomised participants was 25.5 kg m(-2), and 44.8 % of the participants had a BMI ≥ 25.0 kg m(-2). Food4Me is the first large multi-centre RCT of web-based PN. The main outcomes from the Food4Me study will be submitted for publication during 2015.
Language eng
DOI 10.1007/s12263-014-0450-2
Field of Research 111199 Nutrition and Dietetics not elsewhere classified
Socio Economic Objective 920411 Nutrition
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Springer-Verlag Berlin Heidelberg
Persistent URL http://hdl.handle.net/10536/DRO/DU:30082998

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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