Influence of base on nitro-aldol (Henry) reaction products for alternative clandestine pathways
Andrighetto, Luke M., Henderson, Luke C., Pearson, James R., Stevenson, Paul G. and Conlan, Xavier A. 2016, Influence of base on nitro-aldol (Henry) reaction products for alternative clandestine pathways, Australian journal of forensic sciences, vol. 48, no. 6, pp. 684-693, doi: 10.1080/00450618.2015.1112429.
Attached Files
Name
Description
MIMEType
Size
Downloads
Title
Influence of base on nitro-aldol (Henry) reaction products for alternative clandestine pathways
Australian clandestine drug laboratories are constantly utilising alternative methods to produce methamphetamine, in part as restrictions are placed by Government on, for example, chemicals such as phenyl-2-propanone (P2P) (in the early 1980s), or on pseudoephedrine-containing pharmaceuticals, from the mid-2000s. This paper discusses the nitro-aldol reaction occurring between nitroethane and benzaldehyde, which can be utilised in a number of differing routes, in the presence of different bases. The resulting products, namely phenyl-2-nitropropene (P2P pathway) and 2-nitro-1-phenyl-1-propanol (ephedrine pathway) are directly dependant on which base is used; as such, the base may be used to provide an indication of a possible manufacture pathway of methamphetamine at a clandestine laboratory.
Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.