Nanoparticulate drug delivery to colorectal cancer : formulation strategies and surface engineering

Tran, Thao Truong-Dinh, Tran, Phuong Ha-Lien, Wang, Yichao, Li, Puwang and Kong, Lingxue 2016, Nanoparticulate drug delivery to colorectal cancer : formulation strategies and surface engineering, Current pharmaceutical design, vol. 22, no. 19, pp. 2904-2912, doi: 10.2174/1381612822666160217140932.

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Title Nanoparticulate drug delivery to colorectal cancer : formulation strategies and surface engineering
Author(s) Tran, Thao Truong-Dinh
Tran, Phuong Ha-LienORCID iD for Tran, Phuong Ha-Lien orcid.org/0000-0001-8463-7516
Wang, Yichao
Li, Puwang
Kong, LingxueORCID iD for Kong, Lingxue orcid.org/0000-0001-6219-3897
Journal name Current pharmaceutical design
Volume number 22
Issue number 19
Start page 2904
End page 2912
Total pages 9
Publisher Bentham Science Publishers
Place of publication Beijing, China
Publication date 2016
ISSN 1873-4286
Keyword(s) nanoparticles
poly (lactide-co-glycolide)
chitosan
colorectal cancer
theranostic
surface engineering
Summary The evolution of polymer-based nanoparticle as a drug delivery carrier has greatly contributed to the development of advanced nano and micro-medicine in the past few decades. The polymer-based nanoparticles of biodegradable and biocompatible polymers such as poly (lactide-co-glycolide) and chitosan which have been approved by Food & Drug Administration and/or European Medicine Agency can particularly facilitate the maintaining of specific properties for a real transition from laboratory to the clinical oral and parental administration. This review presents an overview of the strategies of preparing polymeric nanoparticles and using them for targeting colorectal cancer. Theranostics and surface engineering aspects of nanoparticle design in colonic cancer delivery are also highlighted.
Language eng
DOI 10.2174/1381612822666160217140932
Field of Research 091205 Functional Materials
091209 Polymers and Plastics
110102 Medical Biochemistry: Carbohydrates
1115 Pharmacology And Pharmaceutical Sciences
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Bentham Science Publishers
Persistent URL http://hdl.handle.net/10536/DRO/DU:30083435

Document type: Journal Article
Collections: School of Medicine
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