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Ethical considerations in preventive interventions for bipolar disorder.

Ratheesh, A, Cotton, SM, Davey, CG, Adams, S, Bechdolf, A, Macneil, C, Berk, Michael and McGorry, PD 2016, Ethical considerations in preventive interventions for bipolar disorder., Early intervention in psychiatry, vol. 10, pp. 104-112, doi: 10.1111/eip.12340.

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Title Ethical considerations in preventive interventions for bipolar disorder.
Author(s) Ratheesh, A
Cotton, SM
Davey, CG
Adams, S
Bechdolf, A
Macneil, C
Berk, MichaelORCID iD for Berk, Michael
McGorry, PD
Journal name Early intervention in psychiatry
Volume number 10
Start page 104
End page 112
Total pages 9
Publisher Wiley-Blackwell Publishing Asia
Place of publication Milton, Queensland
Publication date 2016-03-30
ISSN 1751-7893
Keyword(s) bipolar
early intervention
Science & Technology
Life Sciences & Biomedicine
Summary AIM: Early intervention and prevention of serious mental disorders such as bipolar disorder has the promise of decreasing the burden associated with these disorders. With increasing early and preventive intervention efforts among cohorts such as those with a familial risk for bipolar disorder, there is a need to examine the associated ethical concerns. The aim of this review was to examine the ethical issues underpinning the clinical research on pre-onset identification and preventive interventions for bipolar disorder. METHODS: We undertook a PubMed search updated to November 2014 incorporating search terms such as bipolar, mania, hypomania, ethic*(truncated), early intervention, prevention, genetic and family. RESULTS: Fifty-six articles that were identified by this method as well as other relevant articles were examined within a framework of ethical principles including beneficence, non-maleficence, respect for autonomy and justice. The primary risks associated with research and clinical interventions include stigma and labelling, especially among familial high-risk youth. Side effects from interventions are another concern. The benefits of preventive or early interventions were in the amelioration of symptoms as well as the possibility of minimizing disability, cognitive impairment and progression of the illness. Supporting the autonomy of individuals and improving access to stigma-free care may help moderate the potential challenges associated with the risks of interventions. CONCLUSIONS: Concerns about the risks of early identification and pre-onset interventions should be balanced against the potential benefits, the individuals' right to choice and by improving availability of services that balance such dilemmas.
Language eng
DOI 10.1111/eip.12340
Field of Research 110319 Psychiatry (incl Psychotherapy)
1103 Clinical Sciences
1701 Psychology
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, John Wiley & Sons Australia
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Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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