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Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis: a randomised controlled trial

Munukka, M, Waller, B, Rantalainen, T, Häkkinen, A, Nieminen, MT, Lammentausta, E, Kujala, UM, Paloneva, J, Sipilä, S, Peuna, A, Kautiainen, H, Selänne, H, Kiviranta, I and Heinonen, A 2016, Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis: a randomised controlled trial, Osteoarthritis and cartilage, vol. 24, no. 10, pp. 1708-1717, doi: 10.1016/j.joca.2016.05.007.

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Title Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis: a randomised controlled trial
Author(s) Munukka, M
Waller, B
Rantalainen, TORCID iD for Rantalainen, T orcid.org/0000-0001-6977-4782
Häkkinen, A
Nieminen, MT
Lammentausta, E
Kujala, UM
Paloneva, J
Sipilä, S
Peuna, A
Kautiainen, H
Selänne, H
Kiviranta, I
Heinonen, A
Journal name Osteoarthritis and cartilage
Volume number 24
Issue number 10
Start page 1708
End page 1717
Total pages 10
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2016-10
ISSN 1063-4584
1522-9653
Keyword(s) osteoarthritis
aquatic exercise
magnetic resonance imaging (MRI)
cartilage
randomised controlled trial
Summary OBJECTIVE: To study the efficacy of aquatic resistance training on biochemical composition of tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis (OA).

DESIGN: Eighty seven volunteer postmenopausal women, aged 60-68 years, with mild knee OA (Kellgren-Lawrence grades I/II and knee pain) were recruited and randomly assigned to an intervention (n = 43) and control (n = 44) group. The intervention group participated in 48 supervised aquatic resistance training sessions over 16 weeks while the control group maintained usual level of physical activity. The biochemical composition of the medial and lateral tibiofemoral cartilage was estimated using single-slice transverse relaxation time (T2) mapping and delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC index). Secondary outcomes were cardiorespiratory fitness, isometric knee extension and flexion force and knee injury and OA outcome (KOOS) questionnaire.

RESULTS: After 4-months aquatic training, there was a significant decrease in both T2 -1.2 ms (95% confidence interval (CI): -2.3 to -0.1, P = 0.021) and dGEMRIC index -23 ms (-43 to -3, P = 0.016) in the training group compared to controls in the full thickness posterior region of interest (ROI) of the medial femoral cartilage. Cardiorespiratory fitness significantly improved in the intervention group by 9.8% (P = 0.010).

CONCLUSIONS: Our results suggest that, in postmenopausal women with mild knee OA, the integrity of the collagen-interstitial water environment (T2) of the tibiofemoral cartilage may be responsive to low shear and compressive forces during aquatic resistance training. More research is required to understand the exact nature of acute responses in dGEMRIC index to this type of loading. Further, aquatic resistance training improves cardiorespiratory fitness.
Language eng
DOI 10.1016/j.joca.2016.05.007
Field of Research 1103 Clinical Sciences
Socio Economic Objective 920403 Disability and Functional Capacity
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Osteoarthritis Research Society International
Free to Read? Yes
Free to Read Start Date 2017-11-01
Persistent URL http://hdl.handle.net/10536/DRO/DU:30083807

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.