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Low lean tissue mass and physical performance as markers of sarcopenia in older men and women

Pasco, Julie A, Brennan-Olsen, Sharon L, Holloway, Kara L, Hyde, Natalie K and Kotowicz, Mark A 2016, Low lean tissue mass and physical performance as markers of sarcopenia in older men and women, Journal of gerontology and geriatric research, vol. 5, no. 3, pp. 1-4, doi: 10.4172/2167-7182.1000306.

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Title Low lean tissue mass and physical performance as markers of sarcopenia in older men and women
Author(s) Pasco, Julie AORCID iD for Pasco, Julie A orcid.org/0000-0002-8968-4714
Brennan-Olsen, Sharon L
Holloway, Kara L
Hyde, Natalie K
Kotowicz, Mark AORCID iD for Kotowicz, Mark A orcid.org/0000-0002-8094-1411
Journal name Journal of gerontology and geriatric research
Volume number 5
Issue number 3
Start page 1
End page 4
Total pages 4
Publisher OMICS Publishing Group
Place of publication Los Angeles, Calif.
Publication date 2016-05-25
ISSN 2167-7182
Keyword(s) lean mass
skeletal muscle mass
muscle function
physical performance
sarcopenia
ageing
frailty
falls
Summary Background: While declines in muscle mass and function occur in all individuals with advancing age, the extent and rate of decline vary in the general population. We aimed to determine the prevalence of low lean tissue mass combined with poor physical function as an indicator of sarcopenia among older men and women residing in southeastern Australia.

Methods:
The study involved men and women aged 60+ years from the Geelong Osteoporosis Study (GOS). Skeletal muscle mass was measured as total lean tissue mass by dual energy x-ray absorptiometry (DXA) and expressed as a percentage of body weight to generate the skeletal mass index (SMI); low lean mass was defined as SMI T-score <-1. Low muscle function was based on performance using “timed up-and-go” scores >10s. Physical activity scores were determined using a validated questionnaire for the elderly and falls were self-reported for the previous year. Associations between sarcopenia, physical activity and falls were determined using multivariable regression techniques.

Results: Among 624 men, 233 had low SMI, 169 had low muscle performance and 81 had both, thus meeting criteria for sarcopenia. Among 436 women, 143 had low SMI, 179 had low muscle performance and 70 had both. A general age-related increase in the observed prevalence of sarcopenia appeared to be driven by an age-related increase in low performance. Sarcopenia was associated with lower physical activity scores. No association was detected between sarcopenia and falls for men but an association was observed for women (age-adjusted OR 1.87, 95% CI 1.11, 3.14).

Conclusion: In our population, the prevalence of sarcopenia was 10.6% (95% CI 7.7, 13.4) for men and 14.5% (95% CI 10.8, 18.3) for women. Men and women with sarcopenia were habitually less active and, for women, sarcopenia was associated with increased likelihood of falls.
Language eng
DOI 10.4172/2167-7182.1000306
Field of Research 110314 Orthopaedics
Socio Economic Objective 920116 Skeletal System and Disorders (incl. Arthritis)
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30084286

Document type: Journal Article
Collections: Open Access Collection
Molecular and Medical Research
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.