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Pathogenesis of avian influenza: role of the haemagglutinin cleavage site motif

Luczo, Jasmina Maria 2015, Pathogenesis of avian influenza: role of the haemagglutinin cleavage site motif, PhD thesis, School of Medicine, Deakin Univeristy.

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Title Pathogenesis of avian influenza: role of the haemagglutinin cleavage site motif
Author Luczo, Jasmina Maria
Institution Deakin Univeristy
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name PhD
Thesis advisor Bingham, John
Michalski, Wojtek
Stambas, JohnORCID iD for Stambas, John orcid.org/0000-0002-5690-2551
Date submitted 2015-10
Keyword(s) avian influenza
polybasic haemagglutinin cleavage site
Summary  The pathogenicity of highly pathogenic avian influenza viruses (HPAIVs) is highly dependent on the presence of a polybasic haemagglutinin cleavage site (HACS) motif. This study demonstrated that HPAIV replication in chickens occurs primarily in vascular endothelium and is modulated by the molecular composition of the HACS motif.
Language eng
Field of Research 110309 Infectious Diseases
070709 Veterinary Pathology
070712 Veterinary Virology
Socio Economic Objective 920109 Infectious Diseases
Description of original xxxviii, 275, cclxxvi-cccxciii pages : illustrations, tables, graphs, some coloured
Dewey Decimal Classification 616.203
Restricted until 2018-01-18
Copyright notice ┬ęThe author
Free to Read? No
Free to Read Start Date 2018-01-18
Persistent URL http://hdl.handle.net/10536/DRO/DU:30084814

Document type: Thesis
Collection: Higher degree theses (citation only)
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Created: Fri, 08 Jul 2016, 11:32:58 EST by Kate Percival

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