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Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA-Quest): a psychometric study

Busija, L., Buchbinder, R. and Osborne, R.H. 2016, Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA-Quest): a psychometric study, Osteoarthritis and cartilage, vol. 24, no. 8, pp. 1357-1366, doi: 10.1016/j.joca.2016.03.014.

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Title Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA-Quest): a psychometric study
Author(s) Busija, L.
Buchbinder, R.
Osborne, R.H.ORCID iD for Osborne, R.H. orcid.org/0000-0002-9081-2699
Journal name Osteoarthritis and cartilage
Volume number 24
Issue number 8
Start page 1357
End page 1366
Total pages 10
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2016-08
ISSN 1063-4584
1522-9653
Keyword(s) patient-reported outcome measures
osteoarthritis
exploratory factor analysis
confirmatory factor analysis
Rasch modelling
DETERMINANTS
Summary OBJECTIVE: This study reports the development of the OsteoArthritis Questionnaire (OA-Quest) - a new measure designed to comprehensively capture the potentially modifiable burden of osteoarthritis.

DESIGN: Item development was guided by the a priori conceptual framework of the Personal Burden of Osteoarthritis (PBO) which captures 8 dimensions of osteoarthritis burden (Physical distress, Fatigue, Physical limitations, Psychosocial distress, Physical de-conditioning, Financial hardship, Sleep disturbances, Lost productivity). One hundred and twenty three candidate items were pretested in a clinical sample of 18 osteoarthritis patients. The measurement properties of the OA-Quest were assessed with exploratory factor analysis (EFA), Rasch modelling, and confirmatory factor analysis (CFA) in a community-based sample (n = 792).

RESULTS: EFA replicated 7 of the 8 PBO domains. An exception was PBO Fatigue domain, with items merging into the Physical distress subscale in the OA-Quest. Following item analysis, a 42-item 7-subscale questionnaire was constructed, measuring Physical distress (seven items, Cronbach's α = 0.93), Physical limitations (11 items, α = 0.95), Psychosocial distress (seven items, α = 0.93), Physical de-conditioning (four items, α = 0.87), Financial hardship (four items, α = 0.93), Sleep disturbances (five items, α = 0.96), and Lost productivity (four items α = 0.90). A highly restricted 7-factor CFA model had excellent fit with the data (χ(2)(113) = 316.36, P < 0.001; chi-square/degrees of freedom = 2.8; comparative fit index [CFI] = 0.97; root mean square error of approximation [RMSEA] = 0.07), supporting construct validity of the new measure.

CONCLUSIONS: The OA-Quest is a new measure of osteoarthritis burden that is founded on a comprehensive conceptual model. It has strong evidence of construct validity and provides reliable measurement across a broad range of osteoarthritis burden.
Language eng
DOI 10.1016/j.joca.2016.03.014
Field of Research 111799 Public Health and Health Services not elsewhere classified
1103 Clinical Sciences
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Osteoarthritis Research Society International
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30085249

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.