Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma) Singh, Narinderbir 2015, Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma), PhD. thesis, School of Medicine, Deakin University. Attached Files Name Description MIMEType Size Downloads Title Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma) Author Singh, Narinderbir Institution Deakin University School School of Medicine Faculty Faculty of Health Degree type Research doctorate Degree name PhD. Thesis advisor Kanwar (nee Kaur), Rupinder Kanwar Jagat orcid.org/0000-0003-3728-9568 Barrow, Colin orcid.org/0000-0002-2153-7267 Date submitted 2015-09 Keyword(s) Chemotherapy Radiotherapy Cancer Cell biology Summary The study unprecendently provided evidence about the molecular understanding of a dedifferentiation phenotype of glioblastoma-a highly aggressive brain tumour with 12-15 months of patient survival after diagnosis. Further, the efficacies of survivin targeting molecules SurR9-C84A and a natural non-toxic protein bovine lactoferrin as a safe bio-drug to target glioblastoma were evaluated Language eng Field of Research 111201 Cancer Cell Biology 111204 Cancer Therapy (excl Chemotherapy and Radiation Therapy) Socio Economic Objective 920102 Cancer and Related Disorders Description of original xv, 442 pages : illustrations, graphs, tables, some coloured Restricted until 2022-02-21 Copyright notice ©The Author. All Rights Reserved. Persistent URL http://hdl.handle.net/10536/DRO/DU:30085421 Document type: Thesis Collection: Higher degree theses (citation only)   Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 15 Aug 2016, 16:06:21 EST Tue, 16 Aug 2016, 10:56:42 EST Mon, 21 Nov 2016, 12:51:47 EST Mon, 21 Nov 2016, 12:54:22 EST Thu, 09 Mar 2017, 09:18:36 EST Mon, 31 Jul 2017, 15:53:29 EST Fri, 17 Aug 2018, 08:54:48 EST Thu, 23 Aug 2018, 09:04:08 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 195 Abstract Views, 8 File Downloads  -  Detailed Statistics Created: Mon, 15 Aug 2016, 16:06:06 EST by Prue Plummer

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