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Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma)

Singh, Narinderbir 2015, Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma), PhD. thesis, School of Medicine, Deakin University.

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Title Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma)
Author Singh, Narinderbir
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name PhD.
Thesis advisor Kanwar (nee Kaur), Rupinder
Kanwar Jagat
Barrow, Colin
Date submitted 2015-09
Keyword(s) Chemotherapy
Radiotherapy
Cancer
Cell biology
Summary The study unprecendently provided evidence about the molecular understanding of a dedifferentiation phenotype of glioblastoma-a highly aggressive brain tumour with 12-15 months of patient survival after diagnosis. Further, the efficacies of survivin targeting molecules SurR9-C84A and a natural non-toxic protein bovine lactoferrin as a safe bio-drug to target glioblastoma were evaluated
Language eng
Field of Research 111201 Cancer Cell Biology
111204 Cancer Therapy (excl Chemotherapy and Radiation Therapy)
Socio Economic Objective 920102 Cancer and Related Disorders
Description of original xv, 442 pages : illustrations, graphs, tables, some coloured
Restricted until 2019-01-21
Copyright notice ┬ęThe author
Free to Read? No
Free to Read Start Date 2019-01-21
Persistent URL http://hdl.handle.net/10536/DRO/DU:30085421

Document type: Thesis
Collection: Higher degree theses (citation only)
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Created: Mon, 15 Aug 2016, 16:06:06 EST by Prue Plummer

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