Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma)
Singh, Narinderbir 2015, Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma), PhD. thesis, School of Medicine, Deakin University.
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Title
Targeting Survivin and molecular regulation of de-differentiated grade IV Astrocytoma (Glioblastoma)
The study unprecendently provided evidence about the molecular understanding of a dedifferentiation phenotype of glioblastoma-a highly aggressive brain tumour with 12-15 months of patient survival after diagnosis. Further, the efficacies of survivin targeting molecules SurR9-C84A and a natural non-toxic protein bovine lactoferrin as a safe bio-drug to target glioblastoma were evaluated
Language
eng
Field of Research
111201 Cancer Cell Biology 111204 Cancer Therapy (excl Chemotherapy and Radiation Therapy)
Socio Economic Objective
920102 Cancer and Related Disorders
Description of original
xv, 442 pages : illustrations, graphs, tables, some coloured
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