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Delivery of fluorouracil and siRNA by mesoporous silica nanoparticles to drug resistant colorectal cancer

Chen, Lijue 2015, Delivery of fluorouracil and siRNA by mesoporous silica nanoparticles to drug resistant colorectal cancer, Ph.D. thesis, Institute for Frontier Materials, Deakin University.

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Title Delivery of fluorouracil and siRNA by mesoporous silica nanoparticles to drug resistant colorectal cancer
Author Chen, Lijue
Institution Deakin University
School Institute for Frontier Materials
Degree type Research doctorate
Degree name Ph.D.
Thesis advisor Kong, Lingxue
Duan Wei
Shigdar Sarah
She, Fenghua (Mary)
Date submitted 2015-11
Keyword(s) colorectal cancer
gene delivery system
drug resistance
nanobiotechnology
Summary  Mesoporous silica nanoparticle based drug and gene delivery system was developed to overcome the acquired drug resistance in colorectal cancer by targeted delivery of anti-cancer drug in the cytoplasm of the cancer cells and silencing the gene expression related to drug resistance.
Language eng
Field of Research 111205 Chemotherapy
111201 Cancer Cell Biology
030405 Molecular Medicine
Socio Economic Objective 920102 Cancer and Related Disorders
Description of original xix, 183 pages : colour illustrations, tables, graphs
Dewey Decimal Classification 616.994347
Copyright notice ┬ęThe author
Persistent URL http://hdl.handle.net/10536/DRO/DU:30085489

Document type: Thesis
Collection: Higher degree theses (citation only)
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Created: Wed, 17 Aug 2016, 14:55:41 EST by Prue Plummer

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