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Comparison of fracture rates between indigenous and non-indigenous populations: a systematic review protocol

Brennan-Olsen, Sharon L., Quirk, Shae E., Leslie, William D., Toombs, Maree, Holloway, Kara L., Hosking, Sarah M., Pasco, Julie A., Doolan, Brianna J., Page, Richard S. and Williams, Lana J. 2016, Comparison of fracture rates between indigenous and non-indigenous populations: a systematic review protocol, BMJ open, vol. 6, no. 8, Article number : e012124, pp. 1-6, doi: 10.1136/bmjopen-2016-012124.

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Title Comparison of fracture rates between indigenous and non-indigenous populations: a systematic review protocol
Author(s) Brennan-Olsen, Sharon L.
Quirk, Shae E.
Leslie, William D.
Toombs, Maree
Holloway, Kara L.ORCID iD for Holloway, Kara L. orcid.org/0000-0001-5064-2990
Hosking, Sarah M.
Pasco, Julie A.ORCID iD for Pasco, Julie A. orcid.org/0000-0002-8968-4714
Doolan, Brianna J.
Page, Richard S.ORCID iD for Page, Richard S. orcid.org/0000-0002-2225-7144
Williams, Lana J.ORCID iD for Williams, Lana J. orcid.org/0000-0002-1377-1272
Journal name BMJ open
Volume number 6
Issue number 8
Season Article number : e012124
Start page 1
End page 6
Total pages 6
Publisher BMJ Group
Place of publication London, Eng.
Publication date 2016
ISSN 2044-6055
Keyword(s) Indigenous
Musculoskeletal
fracture
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
Summary INTRODUCTION: Over recent years, there has been concerted effort to 'close the gap' in the disproportionately reduced life expectancy and increased morbidity experienced by indigenous compared to non-indigenous persons. Specific to musculoskeletal health, some data suggest that indigenous peoples have a higher risk of sustaining a fracture compared to non-indigenous peoples. This creates an imperative to identify factors that could explain differences in fracture rates. This protocol presents our aim to conduct a systematic review, first, to determine whether differences in fracture rates exist for indigenous versus non-indigenous persons and, second, to identify any risk factors that might explain these differences.

METHODS AND ANALYSIS: We will conduct a systematic search of PubMed, OVID, MEDLINE, CINAHL and EMBASE to identify articles that compare all-cause fracture rates at any skeletal site between indigenous and non-indigenous persons of any age. Eligibility of studies will be determined by 2 independent reviewers. Studies will be assessed for methodological quality using a previously published process. We will conduct a meta-analysis and use established statistical methods to identify and control for heterogeneity where appropriate. Should heterogeneity prevents numerical syntheses, we will undertake a best-evidence analysis to determine the level of evidence for differences in fracture between indigenous and non-indigenous persons.

ETHICS AND DISSEMINATION: This systematic review will use published data; thus, ethical permissions are not required. In addition to peer-reviewed publication, findings will be presented at (inter)national conferences, disseminated electronically and in print, and will be made available to key country-specific decision-makers with authority for indigenous health.
Language eng
DOI 10.1136/bmjopen-2016-012124
Field of Research 111799 Public Health and Health Services not elsewhere classified
110314 Orthopaedics
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30085964

Document type: Journal Article
Collections: School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.