Monodisperse aqueous microspheres encapsulating high concentration of l-ascorbic acid: insights of preparation and stability evaluation from straight-through microchannel emulsification Khalid, Nauman, Kobayashi, Isao, Neves, Marcos A., Uemura, Kunihiko, Nakajima, Mitsutoshi and Nabetani, Hiroshi 2015, Monodisperse aqueous microspheres encapsulating high concentration of l-ascorbic acid: insights of preparation and stability evaluation from straight-through microchannel emulsification, Bioscience, biotechnology and biochemistry, vol. 79, no. 11, pp. 1852-1859, doi: 10.1080/09168451.2015.1050988. Attached Files Name Description MIMEType Size Downloads Title Monodisperse aqueous microspheres encapsulating high concentration of l-ascorbic acid: insights of preparation and stability evaluation from straight-through microchannel emulsification Author(s) Khalid, Nauman orcid.org/0000-0002-8045-199X Kobayashi, Isao Neves, Marcos A. Uemura, Kunihiko Nakajima, Mitsutoshi Nabetani, Hiroshi Journal name Bioscience, biotechnology and biochemistry Volume number 79 Issue number 11 Start page 1852 End page 1859 Total pages 8 Publisher Taylor & Francis Place of publication Abingdon, Eng. Publication date 2015 ISSN 1347-6947 Keyword(s) monodisperse microspheres L-ascorbic acid high concentration stability sodium alginate Summary Stabilization of l-ascorbic acid (⌊-AA) is a challenging task for food and pharmaceutical industries. The study was conducted to prepare monodisperse aqueous microspheres containing enhanced concentrations of ⌊-AA by using microchannel emulsification (MCE). The asymmetric straight-through microchannel (MC) array used here constitutes 11 × 104 μm microslots connected to a 10 μm circular microholes. 5-30% (w/w) ⌊-AA was added to a Milli-Q water solution containing 2% (w/w) sodium alginate and 1% (w/w) magnesium sulfate, while the continuous phase constitutes 5% (w/w) tetraglycerol condensed ricinoleate in water-saturated decane. Monodisperse aqueous microspheres with average diameters (dav) of 18.7-20.7 μm and coefficients of variation (CVs) below 6% were successfully prepared via MCE regardless of the ⌊-AA concentrations applied. The collected microspheres were physically stable in terms of their dav and CV for >10 days of storage at 40°C. The aqueous microspheres exhibited ⌊-AA encapsulation efficiency exceeding 70% during the storage. Language eng DOI 10.1080/09168451.2015.1050988 Field of Research 090802 Food Engineering 090805 Food Processing 0601 Biochemistry And Cell Biology 0703 Crop And Pasture Production Socio Economic Objective 860105 Nutraceuticals and Functional Foods HERDC Research category C1.1 Refereed article in a scholarly journal ERA Research output type C Journal article Copyright notice ©2015, Japan Society for Bioscience, Biotechnology, and Agrochemistry Persistent URL http://hdl.handle.net/10536/DRO/DU:30086036 Document type: Journal Article Collection: School of Life and Environmental Sciences Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 09 Sep 2016, 13:27:38 EST Sat, 10 Sep 2016, 05:01:05 EST Sat, 24 Sep 2016, 06:12:15 EST Tue, 25 Oct 2016, 09:16:02 EST Tue, 25 Oct 2016, 09:23:50 EST Thu, 08 Feb 2018, 14:19:06 EST Thu, 08 Feb 2018, 14:19:42 EST Filtered Full Citation counts:   Cited 8 times in TR Web of Science Cited 8 times in Scopus Search Google Scholar Access Statistics: 131 Abstract Views, 3 File Downloads  -  Detailed Statistics Created: Fri, 09 Sep 2016, 13:27:38 EST

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