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Antibacterial activity of the venom of Heterometrus xanthopus

Ahmed, Umair, Mujaddad-ur-Rehman, Malik, Khalid, Nauman, Fawad, Sardar Atiq and Fatima, Anees 2012, Antibacterial activity of the venom of Heterometrus xanthopus, Indian journal of pharmacology, vol. 44, no. 4, pp. 509-511, doi: 10.4103/0253-7613.99332.

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Title Antibacterial activity of the venom of Heterometrus xanthopus
Formatted title Antibacterial activity of the venom of Heterometrus xanthopus
Author(s) Ahmed, Umair
Mujaddad-ur-Rehman, Malik
Khalid, Nauman
Fawad, Sardar Atiq
Fatima, Anees
Journal name Indian journal of pharmacology
Volume number 44
Issue number 4
Start page 509
End page 511
Total pages 3
Publisher Medknow Publications and Media
Place of publication Mumbai, India
Publication date 2012-08
ISSN 0253-7613
1998-3751
Keyword(s) antibiotics
antimicrobial activity
extracts
Heterometrus xanthopus venom
Summary Heterometrus xanthopus (Scorpion) is one of the most venomous and ancient arthropods. Its venom contains anti-microbial peptides like hadrurin, scorpine, Pandinin 1, and Pandinin 2 that are able to effectively kill multidrug-resistant pathogens. The present study was conducted to evaluate the anti-bacterial activity of H. xanthopus venom. Six Gram-positive and Gram-negative bacterial strains were tested against 1/100, 1/10, and 1/1 fractions of distilled water diluted and crude venom. 1/100 and 1/10 dilutions were not successful in any of the six bacterial strains studied while the 1/1 dilution was effective on Bacillus subtilis ATCC 6633, Salmonella typhimurium ATCC 14028, and Pseudomonas aeruginosa ATCC 27853 with highest zone of inhibition were obtained on B. subtilis. Crude venom was effective against Enterococcus faecalis ATCC 14506, B. subtilis, S. typhimurium, and P. aeruginosa. The most effective results were observed on B. subtilis.
Language eng
DOI 10.4103/0253-7613.99332
Field of Research 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
1115 Pharmacology And Pharmaceutical Sciences
Socio Economic Objective 860899 Human Pharmaceutical Products not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2012, Indian Journal of Pharmacology
Free to Read? Yes
Use Rights Creative Commons Attribution Non-Commercial Share Alike licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30086083

Document type: Journal Article
Collections: School of Life and Environmental Sciences
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.