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Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms

Kanwar, Jagat R., Samarasinghe, Rasika M., Kamalapuram, Sishir K. and Kanwar, Rupinder K. 2016, Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms, Mini reviews in medicinal chemistry, doi: 10.2174/1389557516666160219121634.


Title Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms
Author(s) Kanwar, Jagat R.
Samarasinghe, Rasika M.
Kamalapuram, Sishir K.
Kanwar, Rupinder K.
Journal name Mini reviews in medicinal chemistry
Publisher Bentham Science Publishers
Place of publication Beijing, China
Publication date 2016-02-19
ISSN 1389-5575
1875-5607
Summary Increasing evidence suggests that stem cells, a small population of cells with unique self-renewable and tumour regenerative capacity, are aiding tumour re-growth and multidrug resistance. Conventional therapies are highly ineffective at eliminating these cells leading to relapse of disease and formation of chemoresistance tumours. Cancer and stem cells targeted therapies that utilizes nanotherapeutics to delivery anti-cancer drugs to specific sites are continuously investigated. This review focuses on recent research using nanomedicine and targeting entities to eliminate cancer cells and cancer stem cells. Current nanotherapeutics in clinical trials along with more recent publications on targeted therapies are addressed.
Notes In press
Language eng
DOI 10.2174/1389557516666160219121634
Field of Research 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
0304 Medicinal And Biomolecular Chemistry
1115 Pharmacology And Pharmaceutical Sciences
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Bentham Science Publishers
Persistent URL http://hdl.handle.net/10536/DRO/DU:30087414

Document type: Journal Article
Collection: School of Medicine
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Created: Thu, 13 Oct 2016, 13:59:23 EST

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