Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms Kanwar, Jagat R., Samarasinghe, Rasika M., Kamalapuram, Sishir K. and Kanwar, Rupinder K. 2016, Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms, Mini reviews in medicinal chemistry, doi: 10.2174/1389557516666160219121634. Title Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms Author(s) Kanwar, Jagat R. Samarasinghe, Rasika M. Kamalapuram, Sishir K. Kanwar, Rupinder K. Journal name Mini reviews in medicinal chemistry Publisher Bentham Science Publishers Place of publication Beijing, China Publication date 2016-02-19 ISSN 1389-5575 1875-5607 Summary Increasing evidence suggests that stem cells, a small population of cells with unique self-renewable and tumour regenerative capacity, are aiding tumour re-growth and multidrug resistance. Conventional therapies are highly ineffective at eliminating these cells leading to relapse of disease and formation of chemoresistance tumours. Cancer and stem cells targeted therapies that utilizes nanotherapeutics to delivery anti-cancer drugs to specific sites are continuously investigated. This review focuses on recent research using nanomedicine and targeting entities to eliminate cancer cells and cancer stem cells. Current nanotherapeutics in clinical trials along with more recent publications on targeted therapies are addressed. Notes In press Language eng DOI 10.2174/1389557516666160219121634 Field of Research 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified 0304 Medicinal And Biomolecular Chemistry 1115 Pharmacology And Pharmaceutical Sciences Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal ERA Research output type C Journal article Copyright notice ©2016, Bentham Science Publishers Persistent URL http://hdl.handle.net/10536/DRO/DU:30087414 Document type: Journal Article Collection: School of Medicine Related Links Link Description Connect to Elements publication management system Go to link with your DU access privileges   Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Thu, 13 Oct 2016, 13:59:23 EST Fri, 14 Oct 2016, 04:08:39 EST Fri, 14 Oct 2016, 05:12:11 EST Mon, 24 Oct 2016, 10:31:26 EST Tue, 25 Oct 2016, 05:11:13 EST Mon, 14 Nov 2016, 10:55:28 EST Sat, 18 Feb 2017, 01:31:22 EST Mon, 20 Mar 2017, 05:05:38 EST Wed, 19 Apr 2017, 16:34:30 EST Wed, 19 Apr 2017, 16:37:41 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 9 Abstract Views  -  Detailed Statistics Created: Thu, 13 Oct 2016, 13:59:23 EST

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